Tannic Acid

CAS Number 1401-55-4
Molecular Formula C76H52O46
Molecular Weight 1701.206 g/mol
LogP 6.67
  • Tannic acid
  • [(2R,3R,4S,5R,6S)-3,4,5,6-Tetrakis({3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoyl}oxy)oxan-2-yl]methyl 3,4-dihydroxy-5-[(3,4,5-trihydroxybenzoyl)oxy]benzoate (non-preferred name)
  • 1401-55-4
  • Acacia mollissima tannin
  • Acid, tannic
  • Castanea sativa Mill tannin
  • Caswell No. 819
  • EINECS 215-753-2
  • EPA Pesticide Chemical Code 078502
  • FEMA No. 3042
  • Gallotannic acid
  • Glycerite
  • Liquidambar styraciflua
  • Quebracho wood extract
  • Schinopsis lorentzii tannin
  • Tannic acid (Quercus spp.)
  • Tannin from chestnut
  • Tannin from mimosa
  • Tannin from quebracho
  • Tannin from sweet gum
  • NSC 656273
  • Acide tannique
  • d'Acide tannique
  • UNII-28F9E0DJY6
  • 61790-06-5
  • 67167-65-1
  • 73891-88-0
  • 93615-37-3
  • 1041198-33-7
  • 1041198-44-0


HPLC Separation of Phenylephrine with Tannic Acid Formulation

Phenylephrine is a hydrophilic basic compound. Phenylephrine is used primarily as a decongestant in cough composition. Tannic acid is poly-phenolic compound. Tannic acid is also used to produce tannate salts of certain antihistamins and anti-tussives to impart increased stability or slow release properties to the API (active pharmaceutical ingredient). Phenylephrine in the presence of tannic acid is analyzed by mixed-mode HPLC on a Primesep 100 column. Retention time for phenylephrine is controlled by the amount of acetonitrile and buffer concentration. Tannic acid elutes closer to void and not interferes with analysis of phenylephrine. Method can be used with UV, ELSD, CAD or LC/MS detection.

Application Analytes:

Tannic Acid