Taurine

CAS Number 107-35-7
Molecular Formula C2H7NO3S
Molecular Weight 125.140 g/mol
InChI Key XOAAWQZATWQOTB-UHFFFAOYSA-N
LogP -2.66
Synonyms
  • l-Taurine
  • 2-Aminoethane-1-sulfonic acid
  • Ethanesulfonic acid, 2-amino-
  • 107-35-7
  • Taurine
  • Ethanesulfonic acid, 2-amino-
  • 1-Aminoethane-2-sulfonic acid
  • 2-Aminoethanesulfonic acid
  • 2-Aminoethansulfonic acid
  • 2-Aminoethylsulfonic acid
  • 2-Sulfoethylamine
  • NSC 32428
  • Taukard
  • Tauphon
  • taurina
  • β-Aminoethanesulfonic acid
  • β-Aminoethylsulfonic acid
  • Aminoethanesulfonic acid
  • EINECS 203-483-8
  • FEMA No. 3813
  • NCI-C60606
  • Taurinum
  • UNII-1EQV5MLY3D
  • 1-Aminoethane-2-sulfonate
  • 2-Aminoethanesulfonate
  • 2-Aminoethylsulfonate
  • 2-aminoethane-1-sulfonic acid
  • 2-aminoethyl sulfonate
  • Aminoethylsulfonate
  • b-Aminoethylsulfonate
  • b-Aminoethylsulfonic acid
  • beta-Aminoethylsulfonate
  • beta-aminoethylsulfonic acid
  • 2-ammonioethanesulfonate
  • taurine zwitterion
  • 91105-79-2

Applications:


HPLC Separation of Taurine



Taurine (2-aminoethanesulfonic acid) is organic zwitterionic compound. Taurine is a non-essential sulfur-containing amino acid that functions with glycine and gamma-aminobutyric acid as a neurotransmitter. Taurine is incorporated into one of the most abundant bile acids, chenodeoxycholic acid, where it serves to emulsify dietary lipids in the intestine, promoting digestion. It is used in food and pharmaceutical formulations. High polarity and zwitterionic nature of taurine complicates analysis of this compound by reverse-phase chromatography. Two methods for the analysis of taurine are developed on mixed-mode columns. Taurine is retained on Primesep A column by HILIC cation-exchange mechanism and on Primesep D column by HILIC anion-exchange mechanism. Method can be used for fast and effective quantitation of taurine in various products including energy drinks. Method requires ELSD or LC/MS detection due to lack of UV activity for taurine.



Application Analytes:

Taurine
Zwitterion

Retention of Taurine on Obelisc N Column
Taurine, or 2-aminoethanesulfonic acid, is a very polar zwitter-ionic compound. Taurine is used as an additive for various nutrition composition. The polar and zwitter-ionic nature of taurine prevent it from analysis by RP chromatography, in addition to that, taurine is not UV active and cannot be monitored by UV. The analytical method for analysis of taurine was developed on the Obelisc N HILIC/mixed-mode column. This method with some modifications can be used for the analysis of taurine in complex mixtures with a ELSD or a LC/MS detector.

Condition

Column Obelisc N, 4.6x50 mm, 5 µm, 100A
Mobile Phase MeCN
Buffer AmFm pH 3.0
Flow Rate 1.0 ml/min
Detection ELSD
 

Description

Class of Compounds Amino sulfonic acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Taurine
 

Application Analytes:

Taurine
Zwitterion

Retention of Taurine on SHARC Column
Taurine, or 2-aminoethanesulfonic acid, is a very polar zwitter-ionic compound. Taurine is used as an additive for various nutrition composition. The polar and zwitter-ionic nature of taurine prevent it from analysis by RP chromatography, in addition to that, taurine is not UV active and cannot be monitored by UV. The analytical method for analysis of taurine was developed on the SHARC 1 hydrogen-bonding column. This method with some modifications can be used for the analysis of taurine in complex mixtures with a ELSD or a LC/MS detector.

Condition

Column Sharc 1, 4.6x50 mm, 5 µm, 100A
Mobile Phase MeCN/MeOH
Buffer Formic Acid - 0.1%, AmFm - 0.01%
Flow Rate 1.0 ml/min
Detection ELSD
 

Description

Class of Compounds Amino sulfonic acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Taurine
 

Application Analytes:

Taurine