Vanilmandelic Acid

CAS Number 55-10-7
Molecular Formula C9H10O5
Molecular Weight 198.174 g/mol
InChI Key CGQCWMIAEPEHNQ-UHFFFAOYSA-N
LogP -0.2
Synonyms
  • Vanillylmandelic acid
  • dl-4-Hydroxy-3-methoxymandelic acid
  • Vanilmandelic acid
  • 55-10-7
  • 2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetic acid
  • 4-HYDROXY-3-METHOXYMANDELIC ACID
  • 2394-20-9
  • Vanillomandelic acid
  • (+/-)-Vanillylmandelic acid
  • VMA
  • alpha,4-Dihydroxy-3-methoxybenzeneacetic acid
  • CHEBI:20106
  • CGQCWMIAEPEHNQ-UHFFFAOYSA-N
  • Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-
  • HMMA
  • Mandelic acid, 4-hydroxy-3-methoxy-
  • AK126477
  • H-6500
  • 2-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)acetic acid
  • 2-(3-methoxy-4-oxidanyl-phenyl)-2-oxidanyl-ethanoic acid
  • 3-methoxy-4-hydroxymandelic acid
  • Vanillinmandelic Acid
  • DL-vanillomandelic acid
  • DL-vanillylmandelic acid
  • 4'-Hydroxy-3'-methoxymandelic acid
  • dl-3-Methoxy-4-hydroxymandelic acid
  • 3-Methoxy-4-hydroxymandelate
  • 4-Hydroxy-3-methoxy-DL-mandelic acid
  • (4-Hydroxy-3-methoxyphenyl)glycolic acid
  • Benzeneacetic acid, alpha,4-dihydroxy-3-methoxy-
  • EINECS 200-224-0
  • 3-Methoxy-4-hydroxyphenylhydroxyacetic acid
  • (y)-Vanillylmandelic acid
  • Ia(2)Y+/-aIOEa
  • Benzeneacetic acid, ?,4-dihydroxy-3-methoxy-
  • (?)-Vanillylmandelic acid
  • D0D8XF
  • AC1L1B1N
  • AC1Q46AA
  • Lopac0_000602
  • Oprea1_553862
  • MLS002153465
  • Adrenaline Related Compound 2
  • Bio-0247
  • SCHEMBL134326
  • (.+/-.)-Vanilmandelic acid
  • GTPL6645
  • 4-Hydroxy-3-methoxymandelicacid

Applications:


HPLC Separation of Vanilmandelic, Hydroxyindoleacetic, and Homovanillic Acids
HPLC.cloud View on hplc.cloud

Condition 1

Column Newcrom B , 3.2x50 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 20/80%
Buffer H3PO4 - 0.1%
Flow Rate 0.5 ml/min
Detection UV, 275 nm
 
Vanilmandelic, hydroxyindoleacetic and homovanillic acids are metabolites of various neurotransmitters that are used in urine tests to measure the levels of those neurotransmitters in the body. They can be baseline separated on a reverse-phase Primesep D HPLC column by varying the buffers and pH of the mobile phase consisting of water and acetonitrile (MeCN, ACN). UV detection at 230nm.

Condition 2

Column Primesep D, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN
Buffer TFA,  AmFm
Flow Rate 1.0 ml/min
Detection UV, 230 nm
 

Description

Class of Compounds  Acid, Monocarboxylic acid,  Hydrophilic, Ionizable
Analyzing Compounds Vanilmandelic, Hydroxyindoleacetic, Homovanillic Acid
 

Application Analytes:

5-Hydroxyindole-3-Acetic Acid
Homovanillic Acid
Vanilmandelic Acid

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