HPLC Method for Analysis of Propranolol

6 Propranolol is a synthetic, non-cardioselective beta-adrenergic antagonist that is used for the therapy of hypertension, cardiac arrhythmias, angina pectoris, hyperthyroidism, as well as after a heart attack to improve the chance of survival. Dizziness, lightheadedness, or tiredness may occur after the intake of the medication. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Propranolol. The method is UV compatible and can be used as a general approach for analyzing similar compounds.  


Column Primesep 200, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN - 40%
Buffer H3PO4 - 0.1%,
Flow Rate 0.5 ml/min
Detection UV, 270 nm


Class of Compounds Drug,  Acid, Hydrophilic, Ionizable, Supplements
Analyzing Compounds Propranolol

Application Analytes: