Acetophenone

CAS Number 98-86-2
Molecular Formula C8H8O
Molecular Weight 120.152 g/mol
InChI Key KWOLFJPFCHCOCG-UHFFFAOYSA-N
LogP 1.58
Synonyms
  • Acetophenone
  • 1-Phenylethan-1-one
  • Ethanone, 1-phenyl-
  • 98-86-2
  • ethanone, 1-phenyl-
  • 1-Phenyl-1-ethanone
  • 1-Phenylethanone
  • acetofenona
  • Acetophenon
  • Acetylbenzene
  • Hypnone
  • Methyl phenyl ketone
  • NSC 7635
  • NSC 98542
  • Phenyl methyl ketone
  • Benzene, acetyl-
  • EINECS 202-708-7
  • FEMA No. 2009
  • FEMA Number 2009
  • RCRA waste number U004
  • USAF EK-496
  • UNII-RK493WHV10
  • 1-Phenyl-Ethanone
  • 1-Phenylethan-1-one
  • 1-Phenylethanone (acetophenone)
  • 1-Phenylethanone, 9CI
  • Acetofenon
  • Acetyl-Benzene
  • Acetylbenzol
  • Benzoylmethide
  • Dymex
  • FEMA 2009
  • Hypnon
  • Ketone, methyl phenyl
  • Methyl phenyl-Ketone
  • Methylphenylketone
  • Nchem.180-comp5
  • Phenyl
  • Phenylethanone
  • Phenylmethylketone
  • alpha-Acetophenone
  • benzoyl methide

Applications:


Separation of Acetophenone on Newcrom R1 HPLC column

Acetophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Separation of Acetophenone on Newcrom C18 HPLC column
Newcrom R1

This column is available in new type of hardware with only one connection end. Learn more about performance and advantage of this new hardware.



Application Analytes:

Acetophenone

HPLC Method for Phenol - Acetone Production and Impurities

HPLC method for Phenol – Acetone production and impurities

HPLC Method for Phenol - Acetone Production and Impurities

Condition

Column Newcrom R1, 4.6x100 mm, 3 µm, 100A
Mobile Phase Gradient MeCN - 10-100%, 20 min
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 207 nm
 

Description

Class of Compounds Neutral, Basic, Hydrophobic
Analyzing Compounds Phenol, 2-Phenyl-2-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, Dicumyl Peroxide
 

Application Analytes:

Acetophenone
Cumene
Cumene hydroperoxide
Dicumyl peroxide
Phenol