Acrylic acid

Acrylic acid structural formula

CAS Number79-10-7
Molecular FormulaC3H4O2
Molecular Weight72.063
InChI KeyNIXOWILDQLNWCW-UHFFFAOYSA-N
LogP0.35
Synonyms
  • Acrylic acid
  • Prop-2-enoic acid
  • 2-Propenoic acid
  • 79-10-7
  • 2-Propenoic acid
  • Acroleic acid
  • LX 300 (crosslinking agent)
  • 4-02-00-01455
  • Acide acrylique
  • acido acrilico
  • ACRYLSAEURE
  • Acrylsaure
  • Ethylenecarboxylic acid
  • Glacial Acrylic Acid
  • NSC 4765
  • Propenoic acid
  • UN 2218
  • Vinylformic acid
  • Acrylic acid, glacial
  • BRN 0635743
  • Caswell No. 009A
  • EINECS 201-177-9
  • Propene acid
  • RCRA waste number U008
  • Acido acrilio
  • Kyselina akrylova
  • UNII-J94PBK7X8S
  • 55927-87-2
  • 166941-59-9
  • 211862-52-1
  • 1265528-53-7
  • 1453489-99-0
  • 1644624-02-1
  • 1703019-10-6
  • 1873349-31-5
  • 2015239-27-5

Applications:

HPLC Separation of Acrylic Acid and 4- Methoxyphenol on Primesep B Column

September 9, 2019


Acrylic acid in combination with other monomers produces copolymers which are used in manufacturing of various products such as paints, adhesives and plastics. Esters and salts of acrylic acid are known as acrylates. 4-methoxyphenol, also known as mequinol, is an active ingredient in topical drugs and is also used for inhibition of radical polymerization of monomers like acrylates. The two compounds can be separated on a mixed-mode Primesep B column with isocratic method in mobile phase of 20/80 Acetonitrile (ACN) and water with 0.02% phosphoric acid buffer. UV Detection 200nm.
 

 

Condition

Column Primesep B, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer H3PO4 – 0.02 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Acid, Hydrophilic, Ionizable, Antioxidant, Inhibitor, Phenol, Carboxylic acid
Analyzing Compounds  Acrylic Acid,  4- Methoxyphenol, Mequinol

 

Application Column

Primesep B

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
4-Methoxyphenol
Acrylic acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Determination of Acrylic Acid on Primesep B Column

September 5, 2019

Acrylic acid, or propenoic acid, is used in a production of various copolymers for manufacturing of diverse range products. It consists of a vinyl group and a carboxylic acid. Acrylic acid can be retained on a reverse-phase (RP) mixed-mode Primesep B column in under 5 minutes. Primesep B is a reverse-phase column with embedded basic ion-pairing groups.

 

Condition

Column Primesep B, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 10/90%
Buffer H3PO4 – 0.1 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm

 

Description

Class of Compounds
Acid, Hydrophilic, Ionizable, Carboxylic acid
Analyzing Compounds Acrylic Acid

 

Application Column

Primesep B

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Acrylic acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Acrylic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Acrylic acid on Newcrom C18 HPLC column

Acrylic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Acrylic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.