HPLC Method for Analysis of Atorvastatin

HPLC Method for Atorvastatin, Lipitor on Newcrom R1 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Atorvastatin, Lipitor 

Atorvastatin is a prescription medication that has C33H35FN2O5 as its molecular formula. It is typically used to lower cholesterol, therefore reducing the risk of heart disease. Grapefruit juice can interfere with this medication.

Atorvastatin, Lipitor can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a phosphoric acid buffer. Detection is performed using UV.

ColumnNewcrom R1, 3.2 x 100 mm, 5 µm, 100 A, dual ended
Mobile PhaseMeCN/H2O – 50/50%
BufferH3PO4 – 0.1 %
Flow Rate0.5 ml/min
DetectionUV, 270 nm
Class of Compounds
Drug, Statin, Hydrophobic, Ionizable
Analyzing CompoundsAtorvastatin, Lipitor

Application Column

Newcrom R1

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Atorvastatin
Lipitor
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.