Butorphanol

CAS Number 42408-82-2
Molecular Formula C21H29NO2
Molecular Weight 327.468 g/mol
InChI Key IFKLAQQSCNILHL-QHAWAJNXSA-N
LogP 3.57
Synonyms
  • Butorphanol
  • 17-(Cyclobutylmethyl)morphinan-3,14-diol
  • Morphinan-3,14-diol, 17-(cyclobutylmethyl)-
  • 42408-82-2
  • Butorfanol
  • (-)-17-(Cyclobutylmethyl)morphinan-3,14-diol
  • EINECS 255-808-8
  • Butorphanolum
  • UNII-QV897JC36D
  • (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
  • (-)-butorphanol

Applications:


HPLC Method for Analysis of Butorphanol
Chr_1048 Butorphanol is a synthetic morphinan analgesic. It has narcotic antagonist action and is used to manage severe pain and migraines as a supplement for balanced general anesthesia. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Butorphanol. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Condition

Column Primesep 200, 3.2x100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 5-50%
Buffer Gradient H3PO4 - 0.05-0.3%, 5 min, 4 min hold
Flow Rate 0.5 ml/min
Detection UV, 270 nm
   

Description

Class of Compounds Drug,  Acid, Hydrophilic, Ionizable,
Analyzing Compounds Butorphanol


Application Analytes:

Butorphanol