Carbocisteine

CAS Number 638-23-3
Molecular Formula C5H9NO4S
Molecular Weight 179.2 g/mol
InChI Key GBFLZEXEOZUWRN-VKHMYHEASA-N
LogP -3.1
Synonyms
  • S-Carboxymethyl-L-cysteine
  • 638-23-3
  • Carbocisteine
  • carbocysteine
  • carbocistein
  • S-(CARBOXYMETHYL)-L-CYSTEINE
  • Bronchokod
  • Mucolase
  • Mucotab
  • Siroxyl
  • Lisil
  • Mucodyne
  • (R)-S-(Carboxymethyl)cysteine
  • Carbocisteina
  • Carbocisteinum
  • S-(Carboxymethyl)-(R)-cysteine
  • L-3-((Carboxymethyl)thio)alanine
  • H-Cys(carboxymethyl)-OH
  • Transbronchin
  • Lisomucil
  • L-Carbocisteine
  • (L)-2-Amino-3-(carboxymethylthio)propionic acid
  • Mukinyl
  • Fluifort
  • Mucofan
  • Rinatiol
  • UNII-740J2QX53R
  • s-carboxymethyl-cysteine
  • Carboxymethylated Cysteine
  • MFCD00002614
  • 186537-58-6
  • S-Carboxymethylcysteine
  • Mucojet sirup
  • Mucolex sirup
  • Superthiol sirup
  • CHEMBL396416
  • CHEBI:16163
  • GBFLZEXEOZUWRN-VKHMYHEASA-N
  • 740J2QX53R
  • S-Carboxymethyl-L-cysteine, 98%
  • 3-(Carboxymethylthio)-L-alanine
  • Alanine, 3-((carboxymethyl)thio)-, L-
  • Carbocisteine-13C3
  • Chilvax
  • Mucosol
  • PectDrill
  • AHR 3053
  • LJ 206
  • C-1850
  • Carbocisteinum [INN-Latin]
  • Carbocisteina [INN-Spanish]
  • (2R)-2-amino-3-(carboxymethylthio)propanoic acid
  • (R)-2-Amino-3-((carboxymethyl)thio)propanoic acid
  • Q-200796
  • (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid
  • Pulmoclase
  • Carbocit
  • Mucolex
  • Mucopront
  • Mucotron
  • Pectox
  • AHR-3053
  • EINECS 211-327-5
  • L-(Carboxymethyl)cysteine
  • NSC 14156
  • SCMC
  • Carbocisteine [INN]
  • BRN 1725012
  • Carboxymethylenecysteine
  • L.J. 206
  • PSCMC
  • (R)-2-amino-3-(carboxymethylthio)propanoic acid
  • Poly(S-carboxymethylcysteine)
  • l-carbocysteine
  • Carbocysteine [USAN:INN:BAN]
  • Poly(S-carboxymethyl-L-cysteine)
  • L.J.206
  • Mucodyne (TN)
  • DF 1794Y
  • Carbocistein [JAN]
  • AC1L4WQH
  • L-Carbocisteine (JP17)
  • SCHEMBL20854
  • KSC495A3H
  • (2R)-2-Amino-3-[(carboxymethyl)thio]propionic acid
  • Jsp004777
  • CTK3J5033
  • (Carboxymethyl)cysteine-, (L)-
  • DTXSID30110060
  • 3-(Carboxymethylthio)alanine, L-
  • BCP13359
  • ZINC1529732
  • ANW-34746
  • BDBM50213735
  • LJ-206
  • SBB015059
  • AKOS015922826
  • 5-Amino-3-thiadihexanoic acid, (L)-
  • ACM2387599
  • DB04339
  • RL04429
  • RTC-066540
  • 29433-95-2
  • AC-11146
  • ACM186537586
  • AJ-26629
  • AK-81240
  • CC-25404
  • CC-34382
  • SC-19827
  • ST075001
  • AB1007076
  • AX8002883
  • DB-054558
  • ST2414447
  • TC-066540
  • FT-0082568
  • FT-0656306
  • FT-0658269
  • L-Cysteine, S-(carboxymethyl)-, homopolymer
  • KS-00001101
  • C03727
  • D00175
  • (2R)-2-amino-3-(carboxymethylthio)propionic acid
  • C-06527
  • 2-Amino-3-(carboxymethylthio)propionic acid, (L)-
  • I14-2712
  • I14-5234
  • (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
  • UNII-4252LRM78Q component GBFLZEXEOZUWRN-VKHMYHEASA-N
  • (2R)-2-azanyl-3-(2-hydroxy-2-oxoethylsulfanyl)propanoic acid
  • Carbocisteine, European Pharmacopoeia (EP) Reference Standard
  • (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acidS-(carboxymethyl)-L-cysteine

Applications:


HPLC Determination of Carbocisteine on Primesep 100 Column
Carbocisteine Carbocisteine, or carbocysteine, is a drug designed to clear the mucus from the upper and lower airways. It’s primarily available in tablet form. It can be retained on a Primesep 100 Column in about 5 minutes. Primesep 100 is a reverse-phase (RP) mixed-mode column with embedded acidic ion-pairing groups.

Condition

Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer H2SO4 - 0.05 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Acid, Hydrophilic, Ionizable, Carboxylic acid, Drug, Carbocyclic, Amino acid
Analyzing Compounds Carbocisteine
 


Application Analytes:

Carbocisteine
S-(Carboxymethyl)-L-cysteine

HPLC Separation of Mixture of Carbocisteine, Methylparaben & Propylparaben on Primesep 100 Column
Carbocysteine is a medication that reduces the viscosity of mucus making it easier to cough up. Methylparaben and propylparaben are used as preservatives in cosmetics, pharmaceuticals and food. They can be separated in HPLC on a Primesep 100 mixed-mode column by both hydrophobic and ionic properties present on the stationary phase. The analytical method uses acetonitrile (ACN) gradient and water with sulfuric acid (H2SO4) as buffer and UV detected at 200nm.

Condition

Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN  - 2-50%, 20 min
Buffer H2SO4 - 0.05 %
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Drug,  Acid, Hydrophilic, Ionizable, Carboxylic acid, Carbocyclic, Benzoate, Hydroxy Acid, Amino Acid, Hydroxybenzoate, Phenol
Analyzing Compounds Carbocisteine, Methylparaben, Propylparaben
 

Application Analytes:

Carbocisteine
Methylparaben
Methylparaben sodium
Propylparaben
Propylparaben sodium

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