Cetirizine | SIELC

CAS Number	83881-51-0
Molecular Formula	C21H25ClN2O3
Molecular Weight	388.890 g/mol
InChI Key	ZKLPARSLTMPFCP-UHFFFAOYSA-N
LogP	1.70
Synonyms	Cetirizine (2-{4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- 83881-51-0 Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- (2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid Hitrizin Film Tablet Cetirizina Cetirizinum UNII-YO7261ME24 Cetirizin

Applications:

HPLC Method for Analysis of Cetirizine

Cetirizine is a member of the diphenylmethylpiperazine group of antihistamines and it contains L- and D-stereoisomers. The drug is a major metabolite of hydroxyzine, and a racemic selective H1 receptor antagonist. In general use, it treatments of hay fever, allergy symptoms (crying, itching, sneezing, etc.), and angioedema. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Cetirizine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Cetirizine