CAS Number 50-36-2
Molecular Formula C17H21NO4
Molecular Weight 303.358 g/mol
LogP 2.30
  • Cocaine
  • Methyl (2R,3S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
  • 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (2R,3S)-
  • 50-36-2
  • 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R,2R,3S,5S)-
  • (-)-Cocaine
  • (R)-Cocaine
  • 2β-Carbomethoxy-3β-(benzoyloxy)tropane
  • 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, [1R-(exo,exo)]-
  • Benzoylmethylecgonine
  • cocaina
  • l-Cocaine
  • Neurocaine
  • C Carrie
  • 3-(Benzoyloxy)-8-methyl-8-azabicyclo-(3.2.1)octane-2-carboxylic acid methyl ether
  • Bernies
  • 2beta-Carbomethoxy-3beta-benzoxytropane
  • 2-beta-Carbomethoxy-3-beta-benzoxytropane
  • Cocaine, l-
  • Dama blanca
  • EINECS 200-032-7
  • Eritroxilina
  • Erytroxylin
  • Happy trails
  • 3beta-Hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylic acid methyl ester benzoate
  • Kokayeen
  • (1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate
  • Methyl Benzoylecgonine
  • Nose candy
  • Pimp's drug
  • Star dust
  • 3-Tropanylbenzoate-2-carboxylic acid methyl ester
  • White girl or lady
  • Crack cocaine


HPLC Method for Analysis of Cocaine
Chr_1041 Cocaine, also known as coke, is mostly used as a recreational drug. It is a strong stimulant. The drug’s most common appearance in powder form is a salt, usually cocaine hydrochloride. Due to Cocaine rapidly metabolizing in the body, so if it’s ingested/inhaled, its concentration in urine usually does not exceed 10% that of its principal metabolite, benzoylecgonine. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Cocaine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.


Column Primesep 200, 3.2x100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 5-50%
Buffer Gradient H3PO4 - 0.05-0.3%, 5 min, 4 min hold
Flow Rate 0.5 ml/min
Detection UV, 270 nm


Class of Compounds Drug,  Acid, Hydrophilic, Ionizable,
Analyzing Compounds Cocaine

Application Analytes: