16a-Hydroxyestradiol

CAS Number 50-27-1
Molecular Formula C18H24O3
Molecular Weight 288.387 g/mol
InChI Key PROQIPRRNZUXQM-ZXXIGWHRSA-N
LogP 2.45
Synonyms
  • Estriol
  • (16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol
  • Estra-1,3,5(10)-triene-3,16,17-triol, (16alpha,17beta)-
  • 50-27-1
  • E3
  • 4-06-00-07550
  • Estra-1,3,5(10)-triene-3,16,17-triol, (16α,17β)-
  • 1,3,5 (10)-Estratriene-3, 16α, 17β-triol
  • 13β-Methyl-1,3,5(10)-gonatriene-3,16α,17β-triol
  • 16α,17β-Estriol
  • 16α-Estriol
  • 16α-Hydroxyestradiol
  • 3,16α,17β-Estriol
  • 3,16α,17β-Trihydroxyestra-1,3,5(10)-triene
  • Aacifemine
  • Colpogyn
  • Destriol
  • ESTRA-1,3,5(10)-TRIENE-3,16α,17β-TRIOL
  • Estratriol
  • Estriel
  • Follicular hormone hydrate
  • Gynasan
  • Holin V
  • Hormomed
  • Incurin
  • Klimax E
  • Klimoral
  • NSC 12169
  • Oestriol
  • Ortho-Gynest
  • Ovesterin
  • Ovestin
  • Ovo-Vinces
  • Theelol
  • Tridestrin
  • Trihydroxyestrin
  • Triovex
  • BRN 2508172
  • EINECS 200-022-2
  • Estra-1,3,5(10)-triene-3,16alpha,17beta-triol
  • 1,3,5-Estratriene-3beta,16alpha,17beta-triol
  • (16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol
  • Estra-1,3,5(10)-trien-3,16alpha,17beta-triol
  • 3,16alpha,17beta-Estriol
  • 3,16-alpha,17-beta-Estriol
  • Estriol, unconjugated
  • Gynaesan
  • Hormonin
  • 16alpha-Hydroxy-17beta-estradiol
  • 16-alpha-Hydroxyoestradiol
  • NSC-12169
  • Oestra-1,3,5(10)-triene-3,16alpha,17beta-triol
  • Oestra-1,3,5(10)-triene-3,16-alpha,17-beta-triol
  • 1,3,5-Oestratriene-3beta,16alpha,17beta-triol
  • (16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol
  • 3,16-alpha,17-beta-Oestriol
  • Overstin
  • Stiptanon
  • Synapause
  • 3,16-alpha,17-beta-Trihydroxy-delta-1,3,5-estratriene
  • 3,16-alpha,17-beta-Trihydroxyestra-1,3,5(10)-triene
  • 3,16alpha,17beta-Trihydroxy-delta-1,3,5-oestratriene
  • 3,16-alpha,17-beta-Trihydroxy-delta-1,3,5-oestratriene
  • 3,16-alpha,17-beta-Trihydroxyoestra-1,3,5(10)-triene
  • Trihydroxyoestrin
  • Triodurin
  • Estriolo
  • (1S,10R,11S,13R,14R,15S)-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-triene-5,13,14-triol
  • 13b-Methyl-1,3,5(10)-gonatriene-3,16a,17b-triol
  • 16-alpha,17-beta-Estriol
  • 16-alpha,17-beta-Oestriol
  • 16-alpha-Hydroxyestradiol
  • 16a,17b-Estriol
  • 16a-Estriol
  • 16a-Hydroxyestradiol
  • 16alpha,17beta-Estriol
  • 16alpha,17beta-Oestriol
  • 16alpha-Hydroxy-17beta-estradiol
  • 16alpha-Hydroxyoestradiol
  • 16alpha-hydroxyestradiol
  • 3,16a,17b-Estriol
  • 3,16a,17b-Trihydroxyestra-1,3,5(10)-triene
  • 3,16alpha,17beta-Trihydroxy-1,3,5(10)-estratriene
  • 3,16alpha,17beta-Trihydroxyestra-1,3,5(10)-triene
  • 3,16alpha,17beta-trihydroxy-Delta(1,3,5)-estratriene
  • Colpovister
  • Deuslon A
  • Deuslon-A
  • Estra-1,3,5(10)-triene-3,16a,17b-triol
  • Estratriol
  • Hemostyptanon
  • Oekolp
  • Oestratriol
  • Oestriolum
  • Orestin
  • Orgastyptin
  • Ovesterin
  • Ovestinon
  • Ovestrion

Applications:


16a-Hydroxyestradiol Separation on Mixed-Mode HPLC Columns

 

16a-Hydroxyestradiol is an estrogen very similar to estriol, but with three C13 in the 2,3,4 positions. Estriol is often used as a marker for fetal health since it is produced by the adrenal cortex of the fetus.  16a-Hydroxyestradiol was analyzed for a study focused on emerging contaminants in water by the Federal Institute of Hydrology of Koblenz, Germany. It was retained on both Primesep 100 and Obelisc R HPLC Columns. Obelisc R is a mixed-mode column which uses a long hydrophobic chain and multiple ionic groups to fine tune retention. Primesep 100 is a reverse phase column with embedded acidic ion pairing groups. Method is LC/MS compatible and will be effective for achieving unique retention for many pesticides.



Application Analytes:

16a-Hydroxyestradiol