| CAS Number | 90-41-5 |
|---|---|
| Molecular Formula | C12H11N |
| Molecular Weight | 169.228 g/mol |
| InChI Key | TWBPWBPGNQWFSJ-UHFFFAOYSA-N |
| LogP | 2.84 |
| Synonyms |
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Applications:
HPLC Separation of Aminobiphenyls
Aminobiphenyls consist of isomers that differ only in the location of a primary amine group on an aromatic ring. 2-, 3-, and 4-aminobiphenyl are separated on a Primesep D with good peak shape and a short retention time by a mixture of reversed-phase and ion-exclusion interactions. Peak order can be reversed for 2- and 3-aminobiphenyls by using ammonium formate buffer without pH adjustment. The HPLC separations use a mobile phase of water, acetonitrile (MeCN, ACN), ammonium formate buffer or acetic acid (HOAc) with UV detection at 250 nm.
Application Analytes:
2-Aminobiphenyl
3-Aminobiphenyl
4-Aminobiphenyl
HPLC Separation of Aminobiphenyl Isomers in Cation-Exchange Mode
Two isomers of aminobiphenyl were successfully retained and separated in cation-exchange mode on a Primesep S2 column. Primesep S2 column is a HILIC/cation-exchange column that can be operated in HILIC, cation-exchange, and anion-exclusion modes. Method and column are compatible with ELSD/LC/MS and UV and can be used for routine analysis of polar molecules.
| Column | Primesep S2, 4.6x150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O - 5/95% |
| Buffer | AmAc pH 5.0 15 mM |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 270 nm |
| Class of Compounds | Hydrophobic, Ionizable |
| Analyzing Compounds | 2-Aminobiphenyl, 4 -Aminobiphenyl |
Application Analytes:
2-Aminobiphenyl
4-Aminobiphenyl
Separation of Toluidine and Aminobiphenyl Isomers
Toluidine isomers and aminobyphenyl isomers are organic compounds each with a substituted amine group. Primesep 200 was used to separate these isomers. Primesep 200 separates isomers by interacting with polar molecules, retaining basic compounds, and additionally by reverse phase mechanism.
Application Analytes:
2-Aminobiphenyl
4-Aminobiphenyl
m-Toluidine
o-Toluidine
p-Toluidine