2,4,5-Trichlorophenoxyacetic acid

CAS Number 93-76-5
Molecular Formula C8H5Cl3O3
Molecular Weight 255.480 g/mol
InChI Key SMYMJHWAQXWPDB-UHFFFAOYSA-N
LogP 3.31
Synonyms
  • 2,4,5-Trichlorophenoxyacetic acid
  • (2,4,5-Trichlorophenoxy)acetic acid
  • Acetic acid, 2-(2,4,5-trichlorophenoxy)-
  • 93-76-5
  • 2,4,5-T
  • 4-06-00-00973
  • Acetic acid, (2,4,5-trichlorophenoxy)-
  • (2,4,5-Trichlorophenoxy)acetic acid
  • 2,4,5-Trichlorophenoxyacetate
  • Acetic acid, 2-(2,4,5-trichlorophenoxy)-
  • Arbokan
  • BCF-Bushkiller
  • NSC 430
  • Trichlorophenoxyacetic acid
  • Trioxon
  • BRN 2055620
  • Brush Killer
  • Brush RHAP
  • Brush-off 445 low volatile brush killer
  • Brushtox
  • Caswell No. 881
  • Crossbow
  • Decamine 4T
  • Ded-Weed
  • Ded-weed brush killer
  • Ded-weed lv-6 brush kil and t-5 brush kil
  • EINECS 202-273-3
  • Envert-T
  • EPA Pesticide Chemical Code 082001
  • Estercide t-2 and t-245
  • Farmco fence rider
  • Fence rider
  • Fruitone A
  • Inverton 245
  • Line rider
  • Phortox
  • RCRA waste number U232
  • Spontox
  • Super D Weedone
  • Tippontormona
  • Visko Rhap
  • Visko rhap low volatile ester
  • (2,4,5-Trichloor-fenoxy)-azijnzuur
  • (2,4,5-Trichlor-phenoxy)-essigsaeure
  • Acide 2,4,5-trichloro phenoxyacetique
  • Acido (2,4,5-tricloro-fenossi)-acetico
  • Cido (2,4,5-tricloro-fenossi)-acetico
  • Kwas 2,4,5-trojchlorofenoksyoctowy
  • UNII-9Q963S4YMX
  • (2,4,5-Trichlorphenoxy)essigsaeure
  • 2,4,5-Trichlorphenoxyessigsaeure
  • 2-(2,4,5-trichlorophenoxy)acetic acid
  • 2-(2,4,5-trichlorophenoxy)ethanoic acid
  • Esteron 245
  • Trioxone

Applications:


Analysis of 2,4,5-Trichlorophenoxyacetic acid on Primesep and Obelisc HPLC Columns

 

 

2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) is a synthetic auxin and herbicide that was widely used until the 1970s. The EURL (European Union Reference Laboratory) included a QuEChERS (Quick, Easy, Cheap, Rugged, and Safe) method for 2,4,5-T as a target pesticide for EUPT-SRM. Obelisc R and Primesep B2 were used to retain 2,4,5-T and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups while Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. This method is LC/MS compatible and can be used as a general approach for analyzing 2,4,5-T and dozens of other pesticides.

 



Application Analytes:

2,4,5-Trichlorophenoxyacetic acid

HPLC Analysis of 2,4,5-T on Mixed-Mode Columns

 

2,4,5-T is a synthetic herbicide that defoliates broad-leaf plants. It was a major component of Agent Orange, a defoliant used during the Vietnam War. 2,4,5-T has been replaced by dicamba and triclopyr due to its possible toxicity. 2,4,5-T was included in a proficiency test ran by the EURL (European Union Reference Laboratory) using QuEChERS methodology on acidic pesticides. Obelisc R retained 2,4,5-T because it has a long hydrophobic chain and ionic pairing groups. Primesep 100 retains by reverse-phase and with acid ion-pairing groups. Method is LC/MS compatible and same conditions can be used on many different pesticides.



Application Analytes:

2,4,5-Trichlorophenoxyacetic acid