3-Aminobenzoic Acid

CAS Number 99-05-8
Molecular Formula C7H7NO2
Molecular Weight 137.139 g/mol
InChI Key XFDUHJPVQKIXHO-UHFFFAOYSA-N
LogP 0.65
Synonyms
  • Benzoic acid, 3-amino-
  • 3-Aminobenzoic acid
  • 99-05-8
  • 4-14-00-01092
  • 3-Aminobenzenecarboxylic acid
  • 3-AMINOBENZOESAEURE
  • 3-Aminobenzoesaure
  • 3-aminobenzoic acid
  • 3-Carboxyaniline
  • Acide 3-aminobenzoique
  • acido 3-aminobenzoico
  • Aniline-3-carboxylic acid
  • BENZOIC ACID, M-AMINO-
  • m-Aminobenzoic acid
  • m-Anthranilic acid
  • m-Carboxyaniline
  • m-Carboxyphenylamine
  • NSC 15012
  • BRN 0471603
  • EINECS 202-724-4
  • UNII-G2X3B3O37U
  • 3-Aminobenzoate
  • Aniline-3-carboxylate
  • M-Amonibenzoate
  • M-Amonibenzoic acid
  • m-Aminobenzoesaeure
  • 1190921-66-4
  • 915120-54-6

Applications:


HPLC Separation of Isomers of Aminobenzoic Acid
 
Aminobenzoic Acid is an organic acid that can be found in folic acid vitamins, grains, eggs, milk, and meat. Because it absorbs the UV light, it is used in sunscreen with SPF 15 or greater. The acid can cause damage to DNA and skin irritations in rare cases. Primesep 100, a reverse phase column, contains embedded acidic ionizable groups and can retain aminobenzoic acid. The method is UV compatible and can be used as a general approach for analyzing similar compounds.
Isomers of organic compounds usually have very similar properties. Separation of such isomers by HPLC requires intensive screening of various columns and mobile phase conditions. In case of hydrophilic compounds, this task becomes even more challenging due to the lack of or limited retention on traditional reversed-phase (C18 or C8) HPLC columns. Three isomers of aminobenzoic acid (2-aminobenzoic acid, 3-aminobenzoic acid and 4-aminobenzoic acid) were successfully separated on a Primesep 100 reversed-phase/cation-exchange column. Baseline separation within 10 minutes was achieved and produced a perfect peak shapes for all three analytes. The method can be used a generic approach for separation of ionic hydrophobic and ionic basic isomers by mixed-mode chromatography.


Application Analytes:

2-Aminobenzoic Acid
3-Aminobenzoic Acid
4-Aminobenzoic Acid

HPLC Separation of Amino Acids on Obelisc R Column

Closely related compounds like amino acids can be separated on an Obelisc R column by various buffers depending on the amount of baseline separation required. By choosing different buffers, the separation between compounds can be adjusted based on application needs, especially those that require low organic concentration in the mobile phase. UV detection at 250nm. 

Application Analytes:

3-Aminobenzoic Acid
Aspartame
Phenylalanine
Tryptophan

Separation of Isomers of Aminobenzoic Acid



Application Analytes:

2-Aminobenzoic Acid
3-Aminobenzoic Acid
4-Aminobenzoic Acid