Alachlor

CAS Number 15972-60-8
Molecular Formula C14H20ClNO2
Molecular Weight 269.770 g/mol
InChI Key XCSGPAVHZFQHGE-UHFFFAOYSA-N
LogP 3.52
Synonyms
  • Alachlor
  • 2-Chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
  • Acetamide, 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)-
  • 15972-60-8
  • Acetamide, 2-chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)-
  • 2',6'-Diethyl-N-(methoxymethyl)-2-chloroacetanilide
  • 2-Chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide
  • 2-Chloro-2',6'-diethyl-N-methoxymethylacetanilide
  • 2-Chloro-N-(2,6-diethylphenyl)-N-(methoxymethyl)acetamide
  • ACETANILIDE, 2-CHLORO-2',6'-DIETHYL-N- (METHOXYMETHYL)-
  • Acetanilide, 2-chloro-2',6'-diethyl-N-(methoxymethyl)-
  • alachlore
  • alacloro
  • Lasagrin
  • Lasso Microtech
  • Metachlor
  • Methachlor
  • Micro-Tech
  • Perfect
  • Satochlor
  • Alochlor
  • BRN 2944476
  • Caswell No. 011
  • Chimiclor
  • alpha-Chloro-2',6'-diethyl-N-methoxymethylacetanilide
  • 2-Chloro-N-(2,6-diethyl)phenyl-N-methoxymethylacetamide
  • EINECS 240-110-8
  • EPA Pesticide Chemical Code 090501
  • Lasso micro-tech
  • N-(Methoxymethyl)-2,6-diethylchloroacetanilide
  • Pillarzo
  • UNII-24S2S61PXL
  • Chloressigsaeure-N-(methoxymethyl)-2,6-diaethylanilid

Applications:


HPLC Analysis of Alachlor
   
Alachlor is a chloroacetanilide family herbicide which inhibits parts of the gibberellin pathway. The EPA classifies alachlor as slightly toxic and set the maximum contaminant level at 2 ppb. The EU banned alachlor in 2006. Obelisc R was used to retain alachlor and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing alachlor.

Condition

 
Column Obelisc R, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer AmFm pH 3.0
Flow Rate 1.0 ml/min
Detection UV, 250 nm
 

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Alachlor
 

Application Analytes:

Alachlor

Alachlor Separation on Obelisc and Primesep HPLC Columns
Alachlor is a herbicide which inhibits the gibberellin pathway. Use of alachlor is banned by the European Union and the U.S. EPA. The EURL (European Union Reference Laboratory) includes alachlor in a pesticide analysis of teas and chamomile by liquid and gas chromatography. A single multiresidue method was developed using both Primesep B2 and Obelisc R analyze many pesticides. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations, while Primesep B2 contains embedded basic ion-pairing groups. Method is LC/MS compatible and can be used as a general approach for analyzing alachlor.

Condition 1

Column Primesep B2, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Alachlor
 

Application Analytes:

Alachlor

HPLC Method for Analysis of Pesticides: Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin

Condition 1

Column Primesep 100, 3.2x100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 - 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm
 

Condition 2

Column Primesep B2, 3.2x100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 - 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Thiamphenicol, Aniline, Simazine, Alachlor, Thiabendazole, Diazinon, Trifluralin
 

Application Analytes:

Alachlor
Aniline
Diazinon
Simazine
Thiabendazole
Thiamphenicol
Trifluralin