Carbofuran

CAS Number 1563-66-2
Molecular Formula C12H15NO3
Molecular Weight 221.256 g/mol
InChI Key DUEPRVBVGDRKAG-UHFFFAOYSA-N
LogP 2.32
Synonyms
  • Carbofuran
  • 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • 1563-66-2
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • 5-17-04-00048
  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate
  • 2,2-Dimethyl-7-coumaranyl N-methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)
  • Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Chinufur
  • Curaterr
  • Diafuran
  • Diafuran 5G
  • Furadan
  • Furadan 350S
  • Furadan 75WP
  • Furadan F
  • Furadan G
  • Furadan SP 50
  • Methylcarbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Niagara 10242
  • N-Methylcarbofuran
  • NSC 167822
  • Sunfuran
  • Terafuran
  • BRN 1428746
  • Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester
  • Carbofurane
  • Caswell No. 160A
  • Crisfuran
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate
  • EINECS 216-353-0
  • EPA Pesticide Chemical Code 090601
  • Furacarb
  • Kenofuran
  • Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Niagara nia-10242
  • Pillarfuran
  • Karbofuranu
  • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7
  • UNII-SKF77S6Y67
  • Bayer 70143

Applications:


Carbofuran Separation on Obelisc R HPLC Column
Carbofuran is one of the most acutely toxic insecticides used on field crops. It is banned in Europe, Canada, and as of 2009 was banned in the United States. The EURL included carbofuran as a target pesticide for the EUPT-CF9. Obelisc R was used to retain carbofuran and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing carbofuran and other phenoxy acids.

Condition 2

Column Obelisc R, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN - 20%
Buffer AmFm pH 3.0- 20 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran

Carbofuran Separation on Primesep and Obelisc Mixed-Mode HPLC Columns
 
Carbofuran is one of the most acutely toxic insecticides used on field crops. It is banned in Europe, Canada, and as of 2009 was banned in the United States. The EURL (European Union Reference Laboratory), included carbofuran as a target pesticide for the EUPT-CF9 a proficiency test for cereals and feedingstuff that require muli-residue methods. Primesep B2 and Obelisc R were used to retain carbofuran and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing carbofuran and other phenoxy acids.
 

Condition 1

Column Primesep B2, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran

HPLC Separation of Carbofuran on Obelisc R and Primesep 100 Columns
  Carbofuran is an insecticide notable for its high toxicity to vertebrates, especially birds; it is one of the most toxic to humans as well. While band in many countries such as the U.S. and Canada, it can be purchased over-the-counter in some countries such as Kenya. Carbofuran was considered a target pesticide by the EURL (European Union Reference Laboratory) for the EUPT-FF9 2015 a proficiency test for the analysis of a over a hundred pesticides. Obelisc R and Primesep 100 were used to analyze carbofuran. Primesep 100 separates by reverse-phase and utilizing embedded acidic ion-pairing groups. Obelisc R uses long hydrophobic chains and multiple ion-pairing groups.

Condition 1

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3

Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran