Carbofuran

Carbofuran structural formula

CAS Number 1563-66-2
Molecular Formula C12H15NO3
Molecular Weight 221.256 g/mol
InChI Key DUEPRVBVGDRKAG-UHFFFAOYSA-N
LogP 2.32
Synonyms
  • Carbofuran
  • 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • 1563-66-2
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate
  • 5-17-04-00048
  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamate
  • 2,2-Dimethyl-7-coumaranyl N-methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl N-methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
  • 7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, 7-(N-methylcarbamate)
  • Carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Chinufur
  • Curaterr
  • Diafuran
  • Diafuran 5G
  • Furadan
  • Furadan 350S
  • Furadan 75WP
  • Furadan F
  • Furadan G
  • Furadan SP 50
  • Methylcarbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Niagara 10242
  • N-Methylcarbofuran
  • NSC 167822
  • Sunfuran
  • Terafuran
  • BRN 1428746
  • Carbamic acid, methyl-, 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl ester
  • Carbofurane
  • Caswell No. 160A
  • Crisfuran
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
  • 2,3-Dihydro-2,2-dimethylbenzofuranyl-7-N-methylcarbamate
  • EINECS 216-353-0
  • EPA Pesticide Chemical Code 090601
  • Furacarb
  • Kenofuran
  • Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • Niagara nia-10242
  • Pillarfuran
  • Karbofuranu
  • N-Metylokarbaminian 2,3-dwuwodoro-2,2-dwumetylobenzofuranylu-7
  • UNII-SKF77S6Y67
  • Bayer 70143

Applications:


Carbofuran Separation on Obelisc R HPLC Column
Carbofuran is one of the most acutely toxic insecticides used on field crops. It is banned in Europe, Canada, and as of 2009 was banned in the United States. The EURL included carbofuran as a target pesticide for the EUPT-CF9. Obelisc R was used to retain carbofuran and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing carbofuran and other phenoxy acids.

Condition 2

Column Obelisc R, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN - 20%
Buffer AmFm pH 3.0- 20 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran

Carbofuran Separation on Primesep and Obelisc Mixed-Mode HPLC Columns
 
Carbofuran is one of the most acutely toxic insecticides used on field crops. It is banned in Europe, Canada, and as of 2009 was banned in the United States. The EURL (European Union Reference Laboratory), included carbofuran as a target pesticide for the EUPT-CF9 a proficiency test for cereals and feedingstuff that require muli-residue methods. Primesep B2 and Obelisc R were used to retain carbofuran and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing carbofuran and other phenoxy acids.
 

Condition 1

Column Primesep B2, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran

HPLC Separation of Carbofuran on Obelisc R and Primesep 100 Columns
  Carbofuran is an insecticide notable for its high toxicity to vertebrates, especially birds; it is one of the most toxic to humans as well. While band in many countries such as the U.S. and Canada, it can be purchased over-the-counter in some countries such as Kenya. Carbofuran was considered a target pesticide by the EURL (European Union Reference Laboratory) for the EUPT-FF9 2015 a proficiency test for the analysis of a over a hundred pesticides. Obelisc R and Primesep 100 were used to analyze carbofuran. Primesep 100 separates by reverse-phase and utilizing embedded acidic ion-pairing groups. Obelisc R uses long hydrophobic chains and multiple ion-pairing groups.

Condition 1

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3

Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Carbofuran
 

Application Analytes:

Carbofuran

HPLC Separation of Pesticides, Herbicides, Fungicides and Insecticides on Newcrom BH Column
Herbicides are used to control unwanted plants, they are also known as weedkillers. Insecticides are used to kill insects. Fungicides are used to kill parasitic fungi. Pesticide is a more generic term that includes herbicides, fungicides and insecticides in its definition. All are heavily used in agriculture. By using HPLC, many different pesticides can be separated and their retention characteristics controlled using the Newcrom BH mixed-mode column. It can be used with different organic media such as acetonitrile (ACN) or methanol (MeOH). By varying the concentration of organic modifier and using different buffers like sulfuric acid (H2SO4), ammonium formate (AmFm), or formic acid, separation of desired pesticides can be achieved.

Condition

Column Newcrom BH, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN, MeOH
Buffer H2SO4, Formic acid, AmFm pH 3.0
Flow Rate 0.6 ml/min
Detection UV 275 nm

Description

Class of Compounds Pesticides, Herbicides, Fungicides, Insecticides
Analyzing Compounds Monocrotophos, Metribuzin, Bromacil, Carbofuran, 4-Chlorophenoxyacetic acid, Bentazone, Folpet, Fenthion, Fenvalerate, Metrabuzin, Carbofuran, Atrazine, Parathion –methyl, MCPA, Clopyralid, Dicamba, Benthazon, Simazine, Diuron, MCPB, Mecoprop, 4-Chlorophenoxyacetic acid,2,4,5-T


Application Analytes:

2,4,5-Trichlorophenoxyacetic acid
4-CPA
Atrazine
Bentazone-sodium
Carbofuran
Clopyralid
Dicamba
Diuron
Fenvalerate
Folpet
MCPA
MCPB
Mecoprop
Methyl parathion
Monocrotophos
Simazine