Cotinine

CAS Number 486-56-6
Molecular Formula C10H12N2O
Molecular Weight 176.219 g/mol
InChI Key UIKROCXWUNQSPJ-VIFPVBQESA-N
LogP 0.07
Synonyms
  • Cotinine
  • (5S)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one
  • 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-
  • 486-56-6
  • (-)-Cotinine
  • 5-24-02-00504
  • 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (5S)-
  • (S)-Cotinine
  • 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-
  • cotinina
  • S-(-)-Cotinine
  • BRN 0083099
  • EINECS 207-634-9
  • UNII-K5161X06LL
  • (5S)-1-methyl-5-(3-pyridyl)-2-pyrrolidinone
  • (5S)-1-methyl-5-(3-pyridyl)-2-pyrrolidone
  • (5S)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one
  • (5S)-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one
  • (5S)-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
  • (S)-(-)-Cotinine
  • (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
  • 1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
  • Cotininum
  • cotinine

Applications:


HPLC Separation of Cotinine Metabolites



Primesep 200 separates the very hydrophilic cotinine metabolites. Ion-exchange and other polar interactions provide retention for a compound that is difficult to retain on traditional C18 reversed-phase columns. The separation uses a simple mobile phase of water, acetonitrile (MeCN, ACN), and trifluoracetic acid (TFA) with UV detection.



Application Analytes:

Cotinine
Cotinine Metabolites