Dapsone

CAS Number 80-08-0
Molecular Formula C12H12N2O2S
Molecular Weight 248.301 g/mol
InChI Key MQJKPEGWNLWLTK-UHFFFAOYSA-N
LogP 0.97
Synonyms
  • Dapsone
  • 4,4'-Sulfonyldianiline
  • Benzenamine, 4,4'-sulfonylbis-
  • 80-08-0
  • 4,4'-Sulfonyldianiline
  • Benzenamine, 4,4'-sulfonylbis-
  • 1,1'-Sulfonylbis[4-aminobenzene]
  • 4,4'-Dapsone
  • 4,4'-Diaminodiphenyl sulfone
  • 4,4'-Diaminodiphenyl sulphone
  • 4,4'-DIAMINODIPHENYLSULFON
  • 4,4'-Sulfonylbisaniline
  • 4,4'-Sulfonylbisbenzamine
  • 4,4'-Sulfonyldiphenylamine
  • 4,4'-Sulphonyldianiline
  • 4-Aminophenyl sulfone
  • Aniline, 4,4'-sulfonyldi-
  • Aradur 976-1
  • Araldite HT 976
  • Avlosulfon
  • Avlosulphone
  • Bis(4-aminophenyl) sulfone
  • Bis(p-aminophenyl) sulfone
  • Croysulfone
  • Croysulphone
  • Di(4-aminophenyl)sulfone
  • Di(p-aminophenyl) sulfone
  • Diaphenylsulfon
  • Diaphenylsulfone
  • Diphenasone
  • DIPHENYL SULFONE, 4,4'-DIAMINO-
  • Diphone
  • Disulone
  • Dumitone
  • Hardener HT 976
  • Metabolite C
  • Novophone
  • NSC 6091
  • p,p'-Diaminodiphenyl sulfone
  • p,p'-Sulfonyldianiline
  • p-Aminophenyl sulfone
  • Seikacure S
  • Servidapson
  • Sulfona
  • Sulfona-Mae
  • Sulphadione
  • Sumicure S
  • Avlosulfone
  • Bis(p-aminophenyl)sulphone
  • Bis(4-aminophenyl)sulphone
  • BRN 0788055
  • Dapsona
  • Dapsonum
  • Diaminodiphenyl sulfone
  • Diamino-4,4'-diphenyl sulfone
  • p,p-Diaminodiphenyl sulphone
  • Diamino-4,4'-diphenyl sulphone
  • Di(4-aminophenyl) sulfone
  • Di(p-aminophenyl)sulphone
  • Di(4-aminophenyl)sulphone
  • Diaphenylsulphon
  • Diaphenylsulphone
  • N,N'-Diphenyl sulfondiamide
  • DSS (VAN)
  • Dubronax
  • EINECS 201-248-4
  • NCI-C01718
  • NSC-6091
  • NSC 6091D
  • Sulfadione
  • Sulfone, diphenyl, 4,4'-diamino-
  • Sulfone UCB
  • 1,1'-Sulfonylbis(4-aminobenzene)
  • p,p-Sulfonylbisbenzamine
  • p,p-Sulfonylbisbenzenamine
  • 1,1'-Sulphonylbis(4-aminobenzene)
  • 4,4'-Sulphonylbisbenzamine
  • 4,4'-Sulphonylbisbenzenamine
  • Sulphonyldianiline
  • p,p-Sulphonyldianiline
  • Tarimyl
  • 4,4'-Diaminodiphenyl suphone
  • 4,4-Diaminodifenylsulfon
  • Diaminodifenilsulfona
  • UNII-8W5C518302
  • 4,4'-Sulfonylbisbenzenamine
  • DADPS
  • DDS
  • Dapsone
  • p,p-sulphonylbisbenzamine
  • p,p-sulphonylbisbenzenamine
  • 1246638-15-2

Applications:


Separation of Antibiotics in Mixed-mode chromatography

 

A complex mixture of sulphonamide, macrolide, tetracycline and fluoroquinolone antibiotics were separated in one run using mixed-mode chromatography with LC/MS -compatible conditions. All compounds are separated based on reversed-phase and/or ion-exchange mechanism. Method can be used for analysis of various classes of antibiotics and related impurities in different sample matrices (blood, urine, soil, waste water).



Application Analytes:

Carboxymethylcysteine
Chlortetracycline
Dapsone
Flumequine
Josamycin
Marbofloxacin
Norfloxacin
Oxytetracycline
Spiramycin
Sulfamethoxazole
Sulfonamides
Sulphadiazine
Sulphaguanidine
Sulphanilamide
Sulphaquinoxaline
Tetracycline
Tylosin

Analysis of Antibiotic Dapsone and Related Impurities in Mixed-Mode Chromatography

Dapsone is an antibiotic used to treat leprosy and acne. Obelisc R was used to analyze dapsone and its impurities. Obelisc R is a tri-modal reversed-phase, cation- and anion-exchange column. Method is compatible with LC/MS and prep chromatography.



Application Analytes:

Dapsone