Diethylamine

CAS Number 109-89-7
Molecular Formula C4H11N
Molecular Weight 73.139 g/mol
InChI Key HPNMFZURTQLUMO-UHFFFAOYSA-N
LogP 0.58
Synonyms
  • Diethylamine
  • N-Ethylethanamine
  • Ethanamine, N-ethyl-
  • 109-89-7
  • Ethanamine, N-ethyl-
  • DIAETHYLAMIN
  • Diethamine
  • Diethylamin
  • dietilamina
  • N,N-Diethylamine
  • N-Ethylethanamine
  • UN 1154
  • EINECS 203-716-3
  • Dwuetyloamina
  • UNII-B035PIS86W
  • (C2H5)2NH
  • DEA
  • Et2NH

Applications:


Separation of Simple Amines and Ammonia



Primesep A separates ammonia and simple amines (butylamine, diethylamine, ethylamine, methylamine and morpholine) by cation exchange and reversed phase. Primesep A has an embedded strong anionic functional group which helps retain cations by polar and ion-exchange mechanisms. Excellent peak shape results with a mass spec compatible mobile phase of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with evaporative light scattering detection (ELSD).



Application Analytes:

Ammonia
Butylamine
Diethylamine
Ethylamine
Methylamine
Morpholine

Mixed-Mode Retention and Separation of Ammonia, Primary and Secondary Amines on Primesep A Column



Ammonia, primary and secondary amines are common compounds used as building blocks in organic synthesis. Derivatives of this compounds are used in agriculture, pharmaceutical and chemical manufacturing. All compounds in this application are basic and hydrophilic in nature. Problems in analysis include poor peak shape, lack of retention on C18 columns, and absence of chromophores in ammonia, primary and secondary amines. Analysis of hydrophilic amines requires derivatization to provide hydrophobicity/retention and UV activity, ion-pairing reagents to provide retention. Presence of residual silanols will affect peak shape. Ammonia, methylamine, morpholine, ethylamine, diethylamine and butylamine can be analyzed on a Primesep A HPLC column with trifluoroacetic acid in the mobile phase. Compounds in the mixture can be monitored by ELSD.



Application Analytes:

Ammonia
Butylamine
Diethylamine
Ethylamine
Methylamine
Morpholine