Estrone

CAS Number 53-16-7
Molecular Formula C18H22O2
Molecular Weight 270.373 g/mol
InChI Key DNXHEGUUPJUMQT-CBZIJGRNSA-N
LogP 3.13
Synonyms
  • Estrone
  • 3-Hydroxyestra-1,3,5(10)-trien-17-one
  • Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
  • 53-16-7
  • E1
  • 3-08-00-01171
  • Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
  • (+)-Estrone
  • 1,3,5(10)-Estratrien-3-ol-17-one
  • 3-Hydroxy-17-keto-estra-1,3,5-triene
  • 3-Hydroxyestra-1,3,5(10)-trien-17-one
  • 3-Hydroxyestra-1,3,5(10)-triene-17-one
  • 3-Hydroxyoestra-1,3,5(10)-trien-17-one
  • Aquacrine
  • Crinovaryl
  • Cristallovar
  • Crystogen
  • Destrone
  • Disynformon
  • Endofolliculina
  • estrona
  • Estrovarin
  • Estrugenone
  • Estrusol
  • Femestrone Inj.
  • Femestrone injection
  • Femidyn
  • Fermidyn
  • Folikrin
  • Folipex
  • Folisan
  • Follestrine
  • Follestrol
  • Follicular hormone
  • Folliculin
  • Folliculinum
  • Follicunodis
  • Follidrin
  • Glandubolin
  • Hiestrone
  • Hormofollin
  • Hormovarine
  • Kestrone
  • Ketodestrin
  • Ketohydroxyestrin
  • Menagen
  • Menformon
  • NSC 9699
  • Oestrin
  • Oestroform
  • Oestrone
  • Oestroperos
  • Ovifollin
  • Perlatan
  • Solliculin
  • Theelin
  • Thelestrin
  • Thelykinin
  • Thynestron
  • Tokokin
  • Wynestron
  • Δ1,3,5(10)-Estratrien-3-ol-17-one
  • BRN 1915077
  • EINECS 200-164-5
  • delta-1,3,5-Estratrien-3beta-ol-17-one
  • delta-1,3,5-estratrien-3-beta-ol-17-one
  • Estrone-A
  • Fem-O-Gen
  • Folliculine
  • Folliculine benzoate
  • Hormestrin
  • 3-Hydroxy-17-keto-oestra-1,3,5-triene
  • 3-Hydroxy-oestra-1,3,5(10)-trien-17-one
  • Ketohydroxy-estratriene
  • Ketohydroxyoestrin
  • Mestronaq
  • 1,3,5(10)-Oestratrien-3-ol-17-one
  • delta-1,3,5-Oestratrien-3beta-ol-17-one
  • delta-1,3,5-oestratrien-3-beta-ol-17-one
  • Oestronum
  • Unden
  • Estrogenic substance
  • Natural estrogenic substance-estrone
  • Estronum
  • UNII-2DI9HA706A
  • (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6-trien-14-one
  • (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
  • D1,3,5(10)-Estratrien-3-ol-17-one
  • 37242-41-4

Applications:


HPLC Separation of Estrone
  Estrone, also known at oestrone and E1 is a naturally occurring estrogen which is the predominant estrogen in postmenopausal women. It can be found in its long-lived form estrone sulfate. In certain scenarios estrone can be a carcinogen and causes breast pain, nausea, headaches and leg cramps. It was separated on both Obelisc R and Primesep 100 which have unique modes of retention. Method is LC/MS compatible and useful for separating a number of pesticides.  

Condition 1

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3

Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds  Hormone,  Hydrophobic, Ionizable
Analyzing Compounds Estrone
 

Application Analytes:

Estrone