Ethyl Paraben

CAS Number 120-47-8
Molecular Formula C9H10O3
Molecular Weight 166.176 g/mol
InChI Key NUVBSKCKDOMJSU-UHFFFAOYSA-N
LogP 2.47
Synonyms
  • Ethylparaben
  • Ethyl 4-hydroxybenzoate
  • Benzoic acid, 4-hydroxy-, ethyl ester
  • 120-47-8
  • ethyl 4-hydroxybenzoate
  • 4-10-00-00367
  • Benzoic acid, 4-hydroxy-, ethyl ester
  • 4-(Ethoxycarbonyl)phenol
  • 4-Carbethoxyphenol
  • 4-hidroxibenzoato de etilo
  • 4-Hydroxybenzoate d'ethyle
  • 4-HYDROXYBENZOESAEURE-AETHYLESTER
  • 4-Hydroxybenzoic acid ethyl ester
  • Aseptin A
  • Aseptine A
  • Aseptoform E
  • BENZOATE, 4-HYDROXY-, ETHYL
  • Benzoic acid, p-hydroxy-, ethyl ester
  • Bonomold OE
  • Easeptol
  • Ethyl Butex
  • Ethyl nipagin
  • Ethyl paraben
  • ETHYL PARASEPT
  • Ethyl p-hydroxybenzoate
  • Ethyl-4-hydroxybenzoat
  • Mekkings E
  • Mycocten
  • Napagin A
  • Nipagin A
  • Nipazin A
  • NSC 23514
  • NSC 8510
  • p-(Ethoxycarbonyl)phenol
  • p-Carbethoxyphenol
  • p-Hydroxybenzoate ethyl ester
  • p-Hydroxybenzoic acid ethyl ester
  • Sobrol A
  • Solbrol A
  • Tegosept E
  • BRN 1101972
  • Carbethoxyphenol
  • Caswell No. 447
  • EINECS 204-399-4
  • EPA Pesticide Chemical Code 061202
  • Ethyl p-oxybenzoate
  • Ester etylowykwasu p-hydroksybenzoesowego
  • Ethylester kyseliny p-hydroxybenzoove
  • p-Oxybenzoesaeureaethylester
  • UNII-14255EXE39

Applications:


HPLC Analysis of Active Drug and Amino Acids in a Formulation
Polar amino acids are very often used as components of vitamin and supplement composition. Analysis of such complex composition is a challenging task. In this application, 5 amino acids (asparagine, glutamic acid, proline and arginine) and two preservatives (methyl paraben and propyl paraben) are separated on a Primesep 100 reversed-phase cation-exchange column with LC/MS compatible mobile phase. Method does not require ion-pairing reagent in the mobile phase. Compounds are monitored by ELSD and UV. Method is validated for quantitation of underivatized amino acids in complex mixtures. The method is simple and robust and can be used for analysis of various vitamin formulations.

Condition

Column Primesep 100, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer AmFm
Flow Rate 1.0 ml/min
Detection ELSD 50C, UV 250 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements
Analyzing Compounds Glutamic acid, Aspargine,  Proline, Lysine, Arginine, Methyl paraben, Propyl paraben
 

Application Analytes:

Arginine
Asparagine
Ethyl Paraben
Glutamic Acid
Lysine
Methylparaben
Proline

Generic Screening Method for Complex Mixtures

Condition

Column Primesep 200, 4.6*150 mm 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer H2SO4
Flow Rate 1.0 ml/min
Detection UV, 215 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Hormone
Analyzing Compounds Uracil, Epinephrine, DOPA, 2,6-Lutidine, Benzylamine, Hydroxytrypthophan, Homovanillic acid, Phenol, Tryptophan , 2,3-DHBA, Benzoic acid, Methylparaben, Ethylparaben, Toluene, Amitriptyline
 

Application Analytes:

2,3-Dihydroxybenzoic Acid
2,6-Lutidine
Amitriptyline
Benzoic Acid
Benzylamine
DOPA (3,4-dihydroxy-L-phenylalanine)
Epinephrine
Ethyl Paraben
Homovanillic Acid
Hydroxytryptophan
Methylparaben
Phenol
Toluene
Tryptophan
Uracil