Etidronic Acid

CAS Number 2809-21-4
Molecular Formula C2H8O7P2
Molecular Weight 206.027 g/mol
InChI Key DBVJJBKOTRCVKF-UHFFFAOYSA-N
LogP -2.05
Synonyms
  • Etidronic acid
  • (1-Hydroxyethane-1,1-diyl)bis(phosphonic acid)
  • Phosphonic acid, (1-hydroxyethylidene)bis-
  • 2809-21-4
  • Phosphonic acid, (1-hydroxyethylidene)bis-
  • 1,1,1-Ethanetriol diphosphonate
  • 0-02-00-00171
  • (1-HYDROXYAETHYLIDEN)-DIPHOSPHONSAEURE
  • (1-Hydroxyethylidene)-1,1-bis(phosphonic acid)
  • (1-Hydroxyethylidene)-1,1-diphosphonic acid
  • (1-Hydroxyethylidene)bisphosphonic acid
  • (1-Hydroxyethylidene)diphosphonic acid
  • 1-Hydroxy-1,1-diphosphonoethane
  • 1-Hydroxyethane-1,1-bisphophonic acid
  • 1-Hydroxyethane-1,1-bisphosphonic acid
  • 1-Hydroxyethane-1,1-diphosphonic acid
  • 1-Hydroxyethane-1,1-diyldiphosphonic acid
  • 1-Hydroxyethanediphosphonic acid
  • 1-HYDROXYETHYLIDENE BISPHOSPHONIC ACID
  • 1-HYDROXYETHYLIDENE(1,1-DIPHOSPHONIC ACID)
  • 1-Hydroxyethylidene-1,1'-diphosphonic acid
  • 1-Hydroxyethylidene-1,1-diphosphonic acid
  • 1-Hydroxyethylidene-1,1-diphosphoric acid
  • 1-Hydroxyethylidene-1,1-disphosphonic acid
  • Acetodiphosphonic acid
  • Acide etidronique
  • acido etidronico
  • Acidum etidronicum
  • Belclene 660
  • Briquest ADPA 60A
  • Briquest ADPA-A
  • Chelate 101
  • Chelest PH 210
  • Cublen K 60
  • Defloc EH 06
  • Dequest 2010
  • Dequest 2010CS
  • Dequest 2010LA
  • Dequest 2015
  • Dequest Z 010
  • ETHANE-1,1-DIPHOSPHONIC ACID, 1-HYDROXY-
  • Ethane-1-hydroxy-1,1'diphosphonic acid
  • Ethane-1-hydroxy-1,1-diphosphonic acid
  • Ethidronate
  • Ethydronate
  • ETHYLIDENE DIPHOSPHONIC ACID, 1-HYDROXY-
  • Etidronisaure
  • Feliox 115A
  • Feliox CY 115
  • Ferrofos 510
  • HYDROXYETHANE-1-1-DIPHOSPHONIC ACID
  • Hydroxyethanediphosphonic acid
  • HYDROXYETHYLIDENEDIPHOSPHONIC ACID
  • Ksidifon
  • Mascol P 210
  • Masquol P 210
  • Mayoquest 1500
  • NSC 227995
  • Oxyethylidenediphosphonic acid
  • Phosphonic acid, (1-hydroxyethylidene)bis
  • Phosphonic acid, (1-hydroxyethylidene)di-
  • PHOSPHONIC ACID, (1-HYDROXYETHYLIDINE)BIS-
  • Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-
  • Phosphonic acid,(1-hydroxyethylidene)bis
  • Phosphoric acid,(1,hydroxyethlidene)bis-
  • Sequion 10H
  • Tecquest 360
  • Terpil SL
  • Turpinal SL
  • Turpinal SLR
  • Wayplex
  • Xidiphone
  • Xydiphone
  • BRN 1789291
  • EINECS 220-552-8
  • Hydroxyethane-1,1-diphosphonic acid
  • (1-Hydroxyethylene)diphosphonic acid
  • 1-Hydroxyethylidene-1,1-biphosphonate
  • (1-Hydroxyethylidene)diphoshonic acid
  • Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester
  • UNII-M2F465ROXU
  • (1-Hydroxyethylidene)bis(phosphonic acid)
  • (Hydroxyethylidene)diphosphonic acid
  • 1-Hydroxyethane-1,1-diphosphonate
  • 1-Hydroxyethanediphosphonic acid
  • 1-Hydroxyethylidene-1,1-bisphosphonate
  • EHDP
  • Ethane-1-hydroxy-1,1-bisphosphonate
  • Ethane-1-hydroxy-1,1-diphosphonate
  • Etidronsaeure
  • HEDP
  • ethane-1-hydroxy-1,1-bisphosphonic acid
  • etidronate
  • 100511-44-2
  • 103736-66-9
  • 106908-76-3
  • 129130-42-3
  • 138360-84-6
  • 192526-55-9
  • 303177-33-5
  • 51888-66-5
  • 66216-98-6
  • 83047-25-0
  • 853028-38-3
  • 85985-26-8
  • 86159-18-4

Applications:


HPLC Separation of Alendronic, Ibandronic, Etidronic Acids



Dronic acids are bisphosphonates that differ in their alkyl chains. Alendronate (Fosamax) marketed alone is used for osteoporosis and other bone diseases. It is also combined with Vitamin C (Fosavance). A short, 50 mm Primesep SB column separates alendronic, ibandronic, and etidronic acids. The HPLC separation uses a mobile phase of water, acetonitrile (MeCN, ACN), trifluoracetic acid (TFA) or ammonium formate and evaporative light scattering detection (ELSD) at 80°C.



Application Analytes:

Alendronic Acid
Etidronic Acid
Ibandronic Acid