Flumequine

CAS Number 42835-25-6
Molecular Formula C14H12FNO3
Molecular Weight 261.253 g/mol
InChI Key DPSPPJIUMHPXMA-UHFFFAOYSA-N
LogP 1.60
Synonyms
  • Flumequine
  • 9-Fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
  • 1H,5H-Benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5-methyl-1-oxo-
  • 42835-25-6
  • EINECS 255-962-6
  • Flumigal
  • Flumiquil
  • Flumisol
  • Imequyl
  • Flumequino
  • Flumequinum
  • UNII-UVG8VSP2SJ

Applications:


Separation of Antibiotics in Mixed-mode chromatography

 

A complex mixture of sulphonamide, macrolide, tetracycline and fluoroquinolone antibiotics were separated in one run using mixed-mode chromatography with LC/MS -compatible conditions. All compounds are separated based on reversed-phase and/or ion-exchange mechanism. Method can be used for analysis of various classes of antibiotics and related impurities in different sample matrices (blood, urine, soil, waste water).



Application Analytes:

Carboxymethylcysteine
Chlortetracycline
Dapsone
Flumequine
Josamycin
Marbofloxacin
Norfloxacin
Oxytetracycline
Spiramycin
Sulfamethoxazole
Sulfonamides
Sulphadiazine
Sulphaguanidine
Sulphanilamide
Sulphaquinoxaline
Tetracycline
Tylosin

Analysis of Antibiotic Flumequine and Related Impurities in Mixed-Mode Chromatography

 

The antibiotic Flumequine is typically used in veterinary medicine. Flumequine and related impurities have been found in animals later sold for meat. Analysis was performed by by mixed-mode chromatography on Primesep D, a reverse-phase column with embedded basic ion-pairing groups and Obelisc R with multiple separation modes (RP,NP,IE).



Application Analytes:

Flumequine

HPLC Separation of Antibiotics of Group in Mixed-Mode Chromatography

Primesep D was used to separate the antibiotics marbofloxacin, norfloxacin, josamycin, and flumequine. Primesep D is a reverse-phase column with embedded basic ion-pairing groups designed for analysis of plasma. This method is compatible with LC/MS and prep chromatography.



Application Analytes:

Flumequine
Josamycin
Marbofloxacin
Norfloxacin

HPLC Separation of a Complex of Quinolone Antibiotics

Quinolones are a group of synthetic broad-spectrum antibiotics with a wide variety of applications in medicine and veterinary sciences. Some quinolones have been found in food products including fish and shrimp. Primesep 100 was used to separate a mixture of quinolones and achieve baseline separation. Retention was controlled by adjusting acetonitrile in the mobile phase.



Application Analytes:

Ciprofloxacin
Enrofloxacin
Flumequine
Oxolinic acid
Pefloxacin