Folpet

Folpet structural formula

CAS Number 133-07-3
Molecular Formula C9H4Cl3NO2S
Molecular Weight 296.550 g/mol
InChI Key HKIOYBQGHSTUDB-UHFFFAOYSA-N
LogP 2.85
Synonyms
  • Folpet
  • 2-[(Trichloromethyl)sulfanyl]-1H-isoindole-1,3(2H)-dione
  • 1H-Isoindole-1,3(2H)-dione, 2-[(trichloromethyl)thio]-
  • 133-07-3
  • Folpan) (N-(Trichloromethylthio)phthalimide
  • 5-21-11-00118
  • 1H-Isoindole-1,3(2H)-dione, 2-[(trichloromethyl)thio]-
  • 2-[(Trichloromethyl)thio]-1H-isoindole-1,3-(2H)-dione
  • 2-[(Trichloromethyl)thio]-1H-isoindole-1,3(2H)-dione
  • Acryptane
  • Cosan T
  • Fungitrol 11
  • Intercide TMP
  • N-(Trichlormethylthio)phthalimid
  • N-(Trichloromethylthio)phtalimide
  • N-(trichloromethylthio)phthalimide
  • N-(triclorometiltio)ftalimida
  • N-[(Trichloromethyl)thio]phthalimide
  • Orthofaltan 50
  • Orthophaltan
  • Phaltan
  • Phaltane
  • PHTHALIMIDE, N-[(TRICHLOROMETHYL)THIO]-
  • Phthaltan
  • Spolacid
  • Vinicoll
  • Acryptan
  • BRN 0193373
  • Caswell No. 464
  • Cosan I
  • EINECS 205-088-6
  • EPA Pesticide Chemical Code 081601
  • Fungitrol
  • Fungitrol II
  • Murphy's rose fungicide
  • Ortho phaltan 50W
  • Thiophal
  • N-(Trichlormethylthio)phthalimide
  • 2-((Trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione
  • Troysan anti-mildew O
  • N-(Trichlor-methylthio)-phthalamid
  • Trichlormethylthioimid kyseliny ftalove
  • UNII-X5NFK36917
  • N-(trichloromethanesulfenyl)phthalimide
  • N-(trichloromethanesulphenyl)phthalimide
  • folpel
  • trichloromethylthiophthalimide
  • 1135442-81-7
  • 52306-33-9

Applications:


HPLC Separation of Folpet on Obelisc and Primesep Mixed-Mode Columns
 
Folpet is a nonsystemic fungicide which is used to prevent apple scab, cherry leaf spot, rose black spot, and rose mildew. A method for folpet was provided by the EURL-SRM, a proficiency test for sigle residue methods developed by the European Union Reference Laboratory. Folpet was retained and separated from impurities with Obelisc R and Primesep B2 columns. Primesep B2 contains embedded basic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method can be used for dozens of other pesticides and is LC/MS compatible.
 

Condition 1

Column Primesep B2, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Folpet
 

Application Analytes:

Folpet

Folpet Analysis on Primesep 100 and Obelisc R HPLC Columns
  Folpet is a fungicide which is used to prevent a variety of fungal infections such as apple scab, cherry leaf spot, rose black spot, and rose mildew. Folpet was one of many pesticides studied by the EURL-SRM, a proficiency test for single residue methods developed by the European Union Reference Laboratory. Folpet was retained and separated from impurities with Obelisc R and Primesep 100 columns. Primesep 100 contains embedded acidic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method can be used for dozens of other pesticides and is LC/MS compatible.

Condition 1

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3

Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Folpet
 

Application Analytes:

Folpet

HPLC Separation of Pesticides, Herbicides, Fungicides and Insecticides on Newcrom BH Column
Herbicides are used to control unwanted plants, they are also known as weedkillers. Insecticides are used to kill insects. Fungicides are used to kill parasitic fungi. Pesticide is a more generic term that includes herbicides, fungicides and insecticides in its definition. All are heavily used in agriculture. By using HPLC, many different pesticides can be separated and their retention characteristics controlled using the Newcrom BH mixed-mode column. It can be used with different organic media such as acetonitrile (ACN) or methanol (MeOH). By varying the concentration of organic modifier and using different buffers like sulfuric acid (H2SO4), ammonium formate (AmFm), or formic acid, separation of desired pesticides can be achieved.

Condition

Column Newcrom BH, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN, MeOH
Buffer H2SO4, Formic acid, AmFm pH 3.0
Flow Rate 0.6 ml/min
Detection UV 275 nm

Description

Class of Compounds Pesticides, Herbicides, Fungicides, Insecticides
Analyzing Compounds Monocrotophos, Metribuzin, Bromacil, Carbofuran, 4-Chlorophenoxyacetic acid, Bentazone, Folpet, Fenthion, Fenvalerate, Metrabuzin, Carbofuran, Atrazine, Parathion –methyl, MCPA, Clopyralid, Dicamba, Benthazon, Simazine, Diuron, MCPB, Mecoprop, 4-Chlorophenoxyacetic acid,2,4,5-T


Application Analytes:

2,4,5-Trichlorophenoxyacetic acid
4-CPA
Atrazine
Bentazone-sodium
Carbofuran
Clopyralid
Dicamba
Diuron
Fenvalerate
Folpet
MCPA
MCPB
Mecoprop
Methyl parathion
Monocrotophos
Simazine