Gemfibrozil

CAS Number 25812-30-0
Molecular Formula C15H22O3
Molecular Weight 250.338 g/mol
InChI Key HEMJJKBWTPKOJG-UHFFFAOYSA-N
LogP 4.28
Synonyms
  • Gemfibrozil
  • 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
  • Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
  • 25812-30-0
  • Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
  • 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
  • Decrelip
  • gemfibrozilo
  • Gevilon
  • Lopizid
  • Trialmin 900
  • Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-
  • BRN 1881200
  • EINECS 247-280-2
  • Apo-Gemfibrozil
  • Bolutol
  • Cholespid
  • Clearol
  • Elmogan
  • Fetinor
  • Fibratol
  • Fibrocit
  • Gemfibril
  • Gemfibromax
  • Gemlipid
  • Gemnpid
  • Gevilon Uno
  • Hipolixan
  • Innogen
  • Ipolipid
  • Lanaterom
  • Lifibron
  • Lipazil
  • Lipigem
  • Lipizyl
  • Litarek
  • Low-Lip
  • Micolip
  • Normolip
  • Polyxit
  • Progemzal
  • Reducel
  • Regulip
  • Renabrazin
  • Sinelip
  • Synbrozil
  • Taborcil
  • Tentroc
  • Trialmin
  • WL-Gemfibrozil
  • 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
  • Gemfibrozilum
  • UNII-Q8X02027X3
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure

Applications:


HPLC Analysis of Gemfibrozil and Ibuprofen Using Mixed-Mode Chromatography



Gemfibrozil is used to lower cholesterol and triglyceride levels in the blood and Ibuprofen is a common over-the-counter painkiller. Fast separations of these two compounds are obtained on short 50 mm columns. Both Primesep B2 and Primesep D separate by a combination of anion exchange and reversed phase. Retention times on Primesep B2 can be adjusted by changing the percentage of acetonitrile. On Primesep D retention times can be changed by adjusting the percentage of acetonitrile and acetic acid in the mobile phase. The HPLC separations use a mobile phase of water, acetonitrile (MeCN, ACN), ammonium formate and acetic acid (HOAc) with UV detection at 270 nm.



Application Analytes:

Gemfibrozil
Ibuprofen