Guanosine Monophosphate

CAS Number 85-32-5
Molecular Formula C10H14N5O8P
Molecular Weight 363.223 g/mol
InChI Key RQFCJASXJCIDSX-UUOKFMHZSA-N
LogP -1.87
Synonyms
  • 5'-Guanylic acid
  • 85-32-5
  • 5'-Guanylsaure
  • Acide 5'-guanylique
  • acido 5'-guanilico
  • Guanidine monophosphate
  • Guanosine 5'-(dihydrogen phosphate)
  • Guanosine 5'-monophosphate
  • Guanosine 5'-phosphate
  • Guanosine 5'-phosphoric acid
  • Guanosine monophosphate
  • Guanylic acid
  • EINECS 201-598-8
  • Guanosine 5'-monophosphoric acid
  • UNII-16597955EP
  • 5'-GMP
  • E 626
  • Guanosine 5'-phosphorate
  • Guanosine-5'-monophosphate
  • Guanosine-5'-phosphate
  • Guanosine-phosphate
  • Guanylate
  • pG
  • {[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
  • GMP
  • 573-48-8
  • 642-41-1
  • 69-28-3

Applications:


Separation of Nine Nucleotides by Mixed-Mode Chromatography
  Nucleotides are important biological molecules which serve as subunits of nucleic acids. They are composed of a five-carbon sugar, a nitrogenous base, and at least one phosphate group. Nucleotides cannot be retained by reverse-phase chromatography without an ion-pairing reagent due to their highly polar nature. Primesep SB is capable of retaining and separating nine nucleotides. Primesep SB is a reverse-phase column with strong embedded basic ion-pairing groups.

Application Analytes:

Adenosine Diphosphate
Adenosine Monophosphate
Adenosine Triphosphate
Cytidine Diphosphate
Cytidine Monophosphate
Cytidine Triphosphate
Guanosine Diphosphate
Guanosine Monophosphate
Guanosine Triphosphate

Separation of Nucleotide Monophosphates

 

Nucleotides are the monomers of DNA and RNA, composed of a five-carbon sugar, a nitrogenous base, and at least one phosphate group. Primesep SB is a good column for separating these highly polar compounds. Primesep SB is a reverse-phase column with strong embedded basic ion-pairing groups. Retention can me manipulated by adjusting acetonitrile, and the baseline separation can be achieved in under 6 minutes using a gradient. 



Application Analytes:

Adenosine Monophosphate
Cytidine Monophosphate
Guanosine Monophosphate
Inosine Monophosphate
Uridine Monophosphate