Hydroxybenzenesulfonamide

CAS Number 599-71-3
Molecular Formula C6H7NO3S
Molecular Weight 173.191 g/mol
InChI Key BRMDATNYMUMZLN-UHFFFAOYSA-N
LogP 0.48
Synonyms
  • Benzenesulfonamide, N-hydroxy-
  • N-Hydroxybenzenesulfonamide
  • 599-71-3
  • 4-11-00-00093
  • Benzsulfohydroxamic acid
  • BRN 2257368
  • EINECS 209-973-8
  • N-Hydroxybenzenesulfonamide
  • Hydroxylamine, N-(phenylsulfonyl)-
  • NSC 45357
  • N-(Phenylsulfonyl)hydroxylamine
  • UNII-C64L4UMH19

Applications:


Separation of Sulfonamides and Phenylhydrazine by Mixed-Mode HPLC



Primesep 100 separates a mixture of sulfonamides (benzenesulfonamide, chlorobenzenesulfonamide, hydroxybenzenesulfonamide) and hydroxysulphaminophenylhydrazine by a mixture of polar and hydrophobic interactions. The stationary phase’s hydrophobic functionality provides a reversed-phase mechanism while the embedded cation-exchange group provides polar interactions. The separation method uses a mobile phase mixture of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with UV detection at 210 nm. This method is mass spec (LC/MS) and evaporative light scattering (ELSD) compatible.



Application Analytes:

Benzenesulfonamide
Chlorobenzenesulfonamide
Hydroxybenzenesulfonamide
Hydroxysulphaminophenylhydrazine
Sulfanilamide
Sulfonamides

HPLC Separation of Aromatic Sulfonamides and Hydrozine





Application Analytes:

Benzenesulfonamide
Chlorobenzenesulfonamide
Hydroxybenzenesulfonamide
Hydroxysulphaminophenylhydrazine
Sulfanilamide