L-Cysteine

CAS Number 52-90-4
Molecular Formula C3H7NO2S
Molecular Weight 121.151 g/mol
InChI Key XUJNEKJLAYXESH-REOHCLBHSA-N
LogP -2.49
Synonyms
  • L-Cysteine
  • 52-90-4
  • (R)-2-Amino-3-mercaptopropanoic acid
  • (R)-Cysteine
  • 2-Amino-3-mercaptopropionic acid
  • Cystein
  • Cysteine
  • Cysteine, L-
  • CYSTEINE, L-(+)-
  • Half-cystine
  • L-(+)-Cysteine
  • L-Alanine, 3-mercapto-
  • L-cisteina
  • L-Cystein
  • NSC 8746
  • Propanoic acid, 2-amino-3-mercapto-, (R)-
  • Thioserine
  • α-Amino-β-thiolpropionic acid
  • β-Mercaptoalanine
  • alpha-Amino-beta-mercaptopropanoic acid, L-
  • 2-Amino-3-mercaptopropanoic acid, (R)-
  • alpha-Amino-beta-mercaptopropionic acid, L-
  • (R)-2-Amino-3-mercaptopropionic acid
  • alpha-Amino-beta-thiolpropionic acid, L-
  • EINECS 200-158-2
  • FEMA No. 3263
  • Half cystine
  • beta-Mercaptoalanine, L-
  • NSC-8746
  • UNII-K848JZ4886
  • (+)-2-Amino-3-mercaptopropionic acid
  • (2R)-2-amino-3-mercapto-propanoic acid
  • (2R)-2-amino-3-mercaptopropanoate
  • (2R)-2-amino-3-mercaptopropanoic acid
  • (2R)-2-amino-3-sulfanyl-propanoic acid
  • (2R)-2-amino-3-sulfanylpropanoate
  • (2R)-2-amino-3-sulfanylpropanoic acid
  • (R)-(+)-cysteine
  • (R)-2-Amino-3-mercaptopropanoate
  • (R)-2-amino-3-mercapto-Propanoate
  • (R)-2-amino-3-mercapto-Propanoic acid
  • (R)-2-amino-3-mercaptopropanoic acid
  • 2-Amino-3-mercaptopropanoate
  • 2-Amino-3-mercaptopropanoic acid
  • 2-Amino-3-mercaptopropionate
  • 3-Mercapto-L-Alanine
  • Acetylcysteine
  • B-Mercaptoalanine
  • Carbocysteine
  • Cisteina
  • Cisteinum
  • Cysteinum
  • E 920
  • E-920
  • E920
  • FREE CYSTEINE
  • L Cysteine
  • L-2-Amino-3-mercaptopropanoate
  • L-2-Amino-3-mercaptopropanoic acid
  • L-Zystein
  • Polycysteine
  • alpha-Amino-beta-thiolpropionic acid
  • beta-Mercaptoalanine
  • (2R)-2-ammonio-3-mercaptopropanoate
  • L-cysteine zwitterion
  • 154605-72-8
  • 4371-52-2

Applications:


HPLC Application for Simultaneous Separation of Amino Acids, Hydrophilic Acidic and Hydrophobic Neutral Compounds



Mixed-mode chromatography allows separating, in single run, compounds with vastly different properties. A method for separation of amino acids (cysteine, methylcysteine, cystine and dimethylcysteine) in the presence of carboxylic acid (benzoic) and hydrophobic neutral compounds was developed on Primesep 100 mixed-mode column. At lower pH ionization of carboxylic acids is suppressed. Amino acids are retained as basic compound based on reverse phase and cation exchange mechanisms. Carboxylic acids are retained on this column based on weak reverse phase mechanisms. Neutral compounds are retained by reverse phase mechanism as on any other column. Retention time of basic, zwitter-ionic and hydrophobic compound can be adjusted by manipulation of mobile phase composition. ELSD, UV or LC/MS detection can be used based on the properties of analytes and mobile phase selection.



Application Analytes:

2,2-Dimethylcysteine
2-Methylcysteine
Benzoic Acid
Cystine
L-Cysteine
Toluene

HPLC Separation of Mixture of Conditionally Essential Amino Acids on Primesep 100 Column
 

Condition

Column Primesep 100, 4.6x250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 35/75%
Buffer H2SO4 0.05% 12 min hold, gradient 0.05-0.20, 13 min
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Amino acids
 

Application Analytes:

Amino Acids
Arginine
Cysteine
Glycine
L-Cysteine
L-Glutamine
Proline
Tyrosine

HPLC Separation of Mixture of 12 Amino Acids on Primesep 100 Column
 

Condition

Column Primesep 100, 4.6x250 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 35/65%
Buffer H2SO4 0.05% 12 min hold, gradient 0.05-0.20, 13 min
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Amino acids
 

Application Analytes:

Amino Acids
Arginine
Asparagine
Cysteine
D-Isoleucine
D-Leucine
D-Valine
DL-Isoleucine
Histidine
Isoleucine
L-Cysteine
L-Methionine
Leucine
Methionine
Phenylalanine
Proline
Tryptophan
Valine