Malathion

CAS Number 121-75-5
Molecular Formula C10H19O6PS2
Molecular Weight 330.351 g/mol
InChI Key JXSJBGJIGXNWCI-UHFFFAOYSA-N
LogP 2.36
Synonyms
  • Malathion
  • Diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioate
  • Butanedioic acid, 2-[(dimethoxyphosphinothioyl)thio]-, diethyl ester
  • 121-75-5
  • Butanedioic acid, [(dimethoxyphosphinothioyl)thio]-, diethyl ester
  • [(Dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester
  • American Cyanamid 4,049
  • Butanedioic acid, 2-[(dimethoxyphosphinothioyl)thio]-, 1,4-diethyl ester
  • Carbetovur
  • Carbetox
  • Carbofos
  • Carbophos
  • Cimexan
  • Cythion
  • Derbac M
  • Diethyl mercaptosuccinate S-ester with O,O-dimethyl phosphorodithioate
  • DIETHYL MERCAPTOSUCCINATE, ESTER WITH DIMETHYLPHOSPHORODITHIOATE
  • Diethyl(dimethoxyphosphinothioylthio) succinate
  • Ethiolacar
  • Extermathion
  • Forthion
  • Fosfothion
  • Fosfotion
  • Fyfanon
  • Gammaxine
  • Hilthion
  • Hi-Yield
  • Insecticide 4049
  • Insecticide no. 4049
  • Karbofos
  • Malafor
  • Malamar
  • Malasol
  • Malaspray
  • Malataf
  • Malathine
  • Malathion E 50
  • Malathion ULV
  • Malathyl
  • Malathyne
  • malation
  • Malatol
  • Malatol 500CE
  • Maldison
  • Mavidan
  • Mercaptothion
  • Moscarda
  • NSC 6524
  • O,O-Dimethyl S-(1,2-dicarbethoxyethyl) dithiophosphate
  • O,O-Dimethyl-S-(1,2-diethoxycarbonylethyl)-phosphoro dithioate
  • Oleophosphothion
  • Organoderm
  • Ortho Malathion
  • Phosphothion
  • Prioderm
  • Radotion
  • Radotion P 5
  • S-[1,2-Bis(carbethoxy)ethyl] O,O-dimethyl dithiophosphate
  • S-[1,2-Bis(ethoxycarbonyl)ethyl] O,O-dimethyl phosphorodithioate
  • S-[1,2-Bis(ethoxycarbonyl)ethyl] O,O-dimethyl thiophosphate
  • S-1,2-bis(Ethoxycarbonyl)ethyl O,O-dimethylphosphorodithioate
  • Sadofos
  • Sadophos
  • Security
  • Siptox I
  • Succinic acid, mercapto-, diethyl ester, S-ester with O,O-dimethyl phosphorodithioate
  • Suleo M
  • Sumitox
  • Zithiol
  • S-(1,2-Bis(carbethoxy)ethyl) O,O-dimethyl dithiophosphate
  • S-(1,2-Bis(ethoxycarbonyl)ethyl) O,O-dimethyl phosphorodithioate
  • S-1,2-Bis(ethoxycarbonyl)ethyl-O,O-dimethyl thiophosphate
  • BRN 1804525
  • Camathion
  • Carbethoxy malathion
  • Chemathion
  • Compound 4049
  • Detmol MA
  • S-(1,2-Dicarbethoxyethyl) O,O-dimethyldithiophosphate
  • S-(1,2-Dicarbethoxyethyl) O,O-dimethylphosphorodithioate
  • Dicarboethoxyethyl O,O-dimethyl phosphorodithioate
  • S-(1,2-Di(ethoxycarbonyl)ethyl) dimethyl phosphorothiolothionate
  • Diethyl ((dimethoxyphosphinothioyl)thio)butanedioate
  • Diethyl (dimethoxyphosphinothioylthio)succinate
  • Diethyl mercaptosuccinate, O,O-dimethyl dithiophosphate, S-ester
  • Diethyl mercaptosuccinate S-ester with O,O-dimethylphosphorodithioate
  • Diethyl(dimethoxythiophosphorylthio)succinate
  • ((Dimethoxyphosphinothioyl)thio)butanedioic acid diethyl ester
  • O,O-Dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl) dithiophosphate
  • O,O-Dimethyl S-1,2-di(ethoxycarbamyl)ethyl phosphorodithioate
  • Dorthion
  • EINECS 204-497-7
  • Emmatos Extra
  • Fosfotion 550
  • Kill-A-Mite
  • Kop-thion
  • Malacide
  • Malagran
  • Malakill
  • Malaphos
  • Malathiazol
  • Malathion E50
  • Malathon
  • Malatox
  • Malphos
  • Mercaptosuccinic acid diethyl ester
  • NCI-C00215
  • Phosphorodithioic acid, O,O-dimethyl ester, S-ester with diethyl mercaptosuccinate
  • Dithiophosphate de O,O-dimethyle et de S-(1,2-dicarboethoxyethyle)
  • Mercaptotion
  • O,O-Dimethyl-S-1,2-(dicarbaethoxyaethyl)-dithiophosphat
  • O,O-Dimethyl-S-1,2-dikarbetoxylethylditiofosfat
  • O,O-Dwumetylo-S-1,2-bis(karboetoksyetylo)-dwutiofosforan
  • S-(1,2-Bis(aethoxy-carbonyl)-aethyl)-O,O-dimethyl-dithiophosphat
  • S-(1,2-Bis(ethoxy-carbonyl)-ethyl)-O,O-dimethyl-dithiofosfaat
  • S-(1,2-Bis(etossi-carbonil)-etil)-O,O-dimetil-ditiofosfato
  • UNII-U5N7SU872W
  • O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl)
  • O,O-dimethyl S-(1,2-dicarbethoxyethyl)phosphorodithioate
  • O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl
  • O,O-dimethyldithiophosphate diethylmercaptosuccinate
  • diethyl (dimethoxyphosphinothioylthio)succinate
  • 11096-67-6
  • 11130-60-2
  • 12737-19-8
  • 12767-62-3
  • 141263-96-9
  • 75513-83-6

Applications:


HPLC Analysis of Malathion
Malathion is the most widely used organophosphate pesticide used in the U.S.. Used heavily in residential landscaping and in public recreation areas, malathion is often used for fruit fly and mosquito eradication. While not considered toxic to humans, malathion metabolizes to a far more toxic malaoxon. The EURL included malathion as a target pesticide for the EUPT-CF9. Obelisc R was used to retain malathion and separate it from impurities. Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing malathion and other organophosphate insecticides.

Condition 2

Column Obelisc R, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN - 40%
Buffer AmFm pH 3.0- 20 mM
Flow Rate 1.0 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Malathion
 

Application Analytes:

Malathion

Malathion Analysis on Obelisc and Primesep Mixed-Mode HPLC Column
 
Malathion is the most widely used organophosphate pesticide used in the US. Used heavily in residential landscaping and in public recreation areas, malathion is often used for fruit fly and mosquito eradication. While not considered toxic to humans, malathion metabolizes to a far more toxic malaoxon. The EURL (European Union Reference Laboratory), included malathion as a target pesticide for the EUPT-CF9 a proficiency test for cereals and feedingstuff that require muli-residue methods. Primesep B2 and Obelisc R were used to retain malathion and separate it from impurities. Primesep B2 contains embedded basic ion-pairing groups and Obelisc R contains embedded ionic and hydrophobic groups which can assist in fine tuning separations. Method is LC/MS compatible and can be used as a general approach for analyzing malathion, other organophosphate insecticides, and dozens of other pesticides.
 

Condition 1

Column Primesep B2, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min,  7 min hold
Buffer Gradient AmAc pH 4,5- 20-50 mM, 15 min,  7 min hold
Flow Rate 0.4 ml/min
Detection UV, 250 nm
   

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds Malathion
 

Application Analytes:

Malathion