Mandelic Acid

CAS Number 90-64-2
Molecular Formula C8H8O3
Molecular Weight 152.149 g/mol
InChI Key IWYDHOAUDWTVEP-UHFFFAOYSA-N
LogP 0.62
Synonyms
  • Mandelic acid
  • Hydroxy(phenyl)acetic acid
  • Benzeneacetic acid, alpha-hydroxy-
  • 90-64-2
  • Benzeneacetic acid, alpha-hydroxy-
  • (+/-)-2-Hydroxy-2-phenylethanoic acid
  • (+/-)-Mandelic acid
  • (+/-)-alpha-Hydroxybenzeneacetic acid
  • (+/-)-alpha-Hydroxyphenylacetic acid
  • (RS)-Mandelic acid
  • 2-Hydroxy-2-phenylacetic acid
  • 2-Phenyl-2-hydroxyacetic acid
  • 2-Phenylglycolic acid
  • Acide mandelique
  • acido mandelico
  • Almond acid
  • alpha-Hydroxy-Phenylacetic acid
  • Amygdalic acid
  • D,L-MANDELSAEURE
  • DL-Amygdalic acid
  • DL-Hydroxy(phenyl)acetic acid
  • dl-Mandelic acid
  • Mandelsaure
  • NSC 7925
  • Paramandelic acid
  • Phenylglycolic acid
  • Phenylhydroxyacetic acid
  • Uromaline
  • alpha-Hydroxybenzeneacetic acid
  • alpha-Hydroxybenzeneacetic acid, (.+-.)-
  • alpha-Hydroxyphenylacetic acid
  • alpha-Hydroxy-α-toluic acid
  • EINECS 202-007-6
  • EINECS 210-277-1
  • Glycolic acid, phenyl-
  • p-Mandelic acid
  • Racemic mandelic acid
  • alpha-Toluic acid, alpha-hydroxy-
  • 2-Hydroy-2-phenylacetic acid
  • Kyselina 2-fenyl-2-hydroxyethanova
  • Kyselina mandlova
  • UNII-NH496X0UJX
  • (2S)-2-hydroxy-2-phenylacetic acid
  • (RS)-Mandelate
  • 2-Hydroxy-2-phenylacetate
  • 2-Hydroxy-2-phenylethanoate
  • 2-Hydroxy-2-phenylethanoic acid
  • 2-Phenyl-2-hydroxyacetate
  • 2-Phenylglycolate
  • Amygdalate
  • DL-Amygdalate
  • DL-Hydroxy(phenyl)acetate
  • DL-Hydroxy(phenyl)acetic acid
  • DL-Mandelate
  • Mandelate
  • Paramandelate
  • Phenylglycolate
  • Phenylhydroxyacetate
  • a-Hydroxy-a-toluate
  • a-Hydroxy-a-toluic acid
  • a-Hydroxybenzeneacetate
  • a-Hydroxybenzeneacetic acid
  • a-Hydroxyphenylacetate
  • a-Hydroxyphenylacetic acid
  • alpha-Hydroxy-alpha-toluate
  • alpha-Hydroxy-alpha-toluic acid
  • alpha-Hydroxybenzeneacetate
  • alpha-Hydroxyphenylacetate
  • 15769-78-5
  • 611-72-3
  • 71036-61-8

Applications:


Complex Mixture of Acids, Bases, Amino Acids, and Neutral Compounds



Primesep 100 separates a mixture of amino acids (tyrosine, phenylalanine), organic acids (benzoic acid, mandelic acid), amines (benzylamine, pyridine), and neutrals (benzonitrile, toluene) in one HPLC run by combining reversed-phase, cation-exchange, and polar interactions. The method is tunable and peak order can be changed significantly by adjusting acetonitrile and trifluoroacetic acid concentrations. The separation method uses a mobile phase mixture of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) and compatible with UV, mass spec (LC/MS) and evaporative light scattering (ELSD) detection.



Application Analytes:

Amino Acids
Benzoic Acid
Benzonitrile
Benzylamine
Mandelic Acid
Organic Acids
Phenylalanine
Pyridine
Toluene
Tyrosine

HILIC Separation of Carboxylic Acids



Hydrophilic acids are separated on Obelisc N mixed-mode HILIC column. Seven carboxylic acids are separated based on their polarity and pKa values. Changes in ionization states of acids and stationary phase can be used to control elution order of organic and inorganic acids.



Application Analytes:

Fumaric Acid
Hydroxybenzoic Acid
Malic Acid
Mandelic Acid
Methylmalonic Acid
Organic Acids
Succinic Acid
Tartaric Acid