MCPB Analysis Using Obelisc and Primesep Analytical HPLC Columns
MCPB (4-(4-Chloro-methylphenoxy)butanoic acid) is an herbicide used on post-emergence broad-leaf weeds. Its acute toxicity is low to moderate, and has been show to damage liver and kidney tissue. Obelisc R and Primesep 100 were both used to separate MCPB. Primesep 100 is a reverse-phase column with embedded acidic ion-pairing groups while Obelisc R is a mixed-mode column with separates using ionic groups and a long hydrophobic chain. The European Union Reference Laboratory (EURL) included MCPB in an analysis of acidic pesticides using single residue methods. Method is LC/MS compatible and useful for many pesticides.