MCPB

MCPB structural formula

CAS Number 94-81-5
Molecular Formula C11H13ClO3
Molecular Weight 228.670 g/mol
InChI Key LLWADFLAOKUBDR-UHFFFAOYSA-N
LogP 3.30
Synonyms
  • MCPB
  • 4-(4-Chloro-2-methylphenoxy)butanoic acid
  • Butanoic acid, 4-(4-chloro-2-methylphenoxy)-
  • 94-81-5
  • 4-(2-Methyl-4-chlorophenoxy)butyric acid
  • 4-06-00-01996
  • BRN 2215202
  • Caswell No. 558
  • gamma-(4-Chloro-2-methylphenoxy)butyric acid
  • 4-(4-Chloro-2-methylphenoxy)butyric acid
  • (4-Chloro-o-tolyloxy)butyric acid
  • 4-((4-Chloro-o-tolyl)oxy)butyric acid
  • EINECS 202-365-3
  • EPA Pesticide Chemical Code 019201
  • MCP-butyric
  • 2-Methyl-4-chlorophenoxybutyric acid
  • NSC 102796
  • Thitrol
  • Trifolex
  • gamma-MCPB
  • 4-(2-Methyl-4-chlorphenoxy)-buttersaeure
  • 4-(4-Chlor-2-methylphenoxy)-buttersaeure
  • Kyselina 4-(4-chlor-2-methylfenoxy)maselna
  • UNII-OA1Z4N1842
  • 4-(4-chloro-o-tolyloxy)butyric acid

Applications:

MCPB Analysis Using Obelisc and Primesep Analytical HPLC Columns
 
MCPB (4-(4-Chloro-methylphenoxy)butanoic acid) is an herbicide used on post-emergence broad-leaf weeds. Its acute toxicity is low to moderate, and has been show to damage liver and kidney tissue. Obelisc R and Primesep 100 were both used to separate MCPB. Primesep 100 is a reverse-phase column with embedded acidic ion-pairing groups while Obelisc R is a mixed-mode column with separates using ionic groups and a long hydrophobic chain. The European Union Reference Laboratory (EURL) included MCPB in an analysis of acidic pesticides using single residue methods. Method is LC/MS compatible and useful for many pesticides.
 

Condition 1
Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2
Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3
Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description
Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds MCPB
 
Application Analytes:

MCPB