MCPB

MCPB structural formula

CAS Number 94-81-5
Molecular Formula C11H13ClO3
Molecular Weight 228.670 g/mol
InChI Key LLWADFLAOKUBDR-UHFFFAOYSA-N
LogP 3.30
Synonyms
  • MCPB
  • 4-(4-Chloro-2-methylphenoxy)butanoic acid
  • Butanoic acid, 4-(4-chloro-2-methylphenoxy)-
  • 94-81-5
  • 4-(2-Methyl-4-chlorophenoxy)butyric acid
  • 4-06-00-01996
  • BRN 2215202
  • Caswell No. 558
  • gamma-(4-Chloro-2-methylphenoxy)butyric acid
  • 4-(4-Chloro-2-methylphenoxy)butyric acid
  • (4-Chloro-o-tolyloxy)butyric acid
  • 4-((4-Chloro-o-tolyl)oxy)butyric acid
  • EINECS 202-365-3
  • EPA Pesticide Chemical Code 019201
  • MCP-butyric
  • 2-Methyl-4-chlorophenoxybutyric acid
  • NSC 102796
  • Thitrol
  • Trifolex
  • gamma-MCPB
  • 4-(2-Methyl-4-chlorphenoxy)-buttersaeure
  • 4-(4-Chlor-2-methylphenoxy)-buttersaeure
  • Kyselina 4-(4-chlor-2-methylfenoxy)maselna
  • UNII-OA1Z4N1842
  • 4-(4-chloro-o-tolyloxy)butyric acid

Applications:


MCPB Analysis Using Obelisc and Primesep Analytical HPLC Columns
 
MCPB (4-(4-Chloro-methylphenoxy)butanoic acid) is an herbicide used on post-emergence broad-leaf weeds. Its acute toxicity is low to moderate, and has been show to damage liver and kidney tissue. Obelisc R and Primesep 100 were both used to separate MCPB. Primesep 100 is a reverse-phase column with embedded acidic ion-pairing groups while Obelisc R is a mixed-mode column with separates using ionic groups and a long hydrophobic chain. The European Union Reference Laboratory (EURL) included MCPB in an analysis of acidic pesticides using single residue methods. Method is LC/MS compatible and useful for many pesticides.
 

Condition 1

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 25-70%, 15 min
Buffer Gradient AmAc pH 3.0- 30-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 2

Column Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Condition 3

Column Primesep 100, 2.1x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-70%, 15 min
Buffer Gradient AmAc pH 3.0- 20-60 mM, 15 min
Flow Rate 0.4 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds  Insecticide, Herbicide, Fungicide,  Hydrophobic, Ionizable
Analyzing Compounds MCPB
 

Application Analytes:

MCPB

HPLC Separation of Pesticides, Herbicides, Fungicides and Insecticides on Newcrom BH Column
Herbicides are used to control unwanted plants, they are also known as weedkillers. Insecticides are used to kill insects. Fungicides are used to kill parasitic fungi. Pesticide is a more generic term that includes herbicides, fungicides and insecticides in its definition. All are heavily used in agriculture. By using HPLC, many different pesticides can be separated and their retention characteristics controlled using the Newcrom BH mixed-mode column. It can be used with different organic media such as acetonitrile (ACN) or methanol (MeOH). By varying the concentration of organic modifier and using different buffers like sulfuric acid (H2SO4), ammonium formate (AmFm), or formic acid, separation of desired pesticides can be achieved.

Condition

Column Newcrom BH, 3.2x100 mm, 5 µm, 100A
Mobile Phase MeCN, MeOH
Buffer H2SO4, Formic acid, AmFm pH 3.0
Flow Rate 0.6 ml/min
Detection UV 275 nm

Description

Class of Compounds Pesticides, Herbicides, Fungicides, Insecticides
Analyzing Compounds Monocrotophos, Metribuzin, Bromacil, Carbofuran, 4-Chlorophenoxyacetic acid, Bentazone, Folpet, Fenthion, Fenvalerate, Metrabuzin, Carbofuran, Atrazine, Parathion –methyl, MCPA, Clopyralid, Dicamba, Benthazon, Simazine, Diuron, MCPB, Mecoprop, 4-Chlorophenoxyacetic acid,2,4,5-T


Application Analytes:

2,4,5-Trichlorophenoxyacetic acid
4-CPA
Atrazine
Bentazone-sodium
Carbofuran
Clopyralid
Dicamba
Diuron
Fenvalerate
Folpet
MCPA
MCPB
Mecoprop
Methyl parathion
Monocrotophos
Simazine