Metformin

CAS Number 657-24-9
Molecular Formula C4H11N5
Molecular Weight 129.168 g/mol
InChI Key XZWYZXLIPXDOLR-UHFFFAOYSA-N
LogP -1.37
Synonyms
  • Metformin
  • N,N-Dimethyltriimidodicarbonic diamide
  • Imidodicarbonimidic diamide, N,N-dimethyl-
  • 657-24-9
  • Imidodicarbonimidic diamide, N,N-dimethyl-
  • 1,1-Dimethylbiguanide
  • Biguanide, 1,1-dimethyl-
  • Cidophage
  • Dimethylbiguanide
  • Emiphage
  • Ficonax
  • Fluamine
  • Flumamine
  • Gliguanid
  • Haurymelin
  • metformina
  • metformine
  • Metiguanide
  • Metphage
  • N,N-Dimethylbiguanide
  • N,N-Dimethyldiguanide
  • N,N-Dimethylimidodicarbonimidic diamide
  • N,N-Dimethyl-imidodicarbonimidic diamide
  • N1,N1-Dimethylbiguanide
  • N'-Dimethylguanylguanidine
  • Diabetosan
  • Dimethyldiguanide
  • EINECS 211-517-8
  • Glifage
  • Islotin
  • Metforminum
  • UNII-9100L32L2N
  • 1,1-Dimethyl biguanide
  • 1-carbamimidamido-N,N-dimethylmethanimidamide
  • DMBG
  • Diabefagos
  • Diabex
  • Diaformin
  • Dianben
  • Fortamet
  • Glucophage
  • Glumetza
  • Meguan
  • Metformin
  • Obimet
  • Riomet

Applications:


HPLC Analysis of Metformin

chr_287.gif

Metformin is a biguanide-based anti-diabetic drug. It is a very polar organic compound that has no retention on reversed-phase column unless an ion-pairing reagent is employed. Metformin was retained on a Primesep 200 column based on cation-exchange mechanism. Method can be used for analysis of metformin and related substances in pharmaceutical formulations. Due to low UV activity a more UV-transparent mobile phase is required. Metformin can be also monitored by ELSD and LC/MS with corresponding mobile phase (TFA, ammonium formate or ammonium acetate).



Application Analytes:

Metformin