Nutrasweet

CAS Number 22839-47-0
Molecular Formula C14H18N2O5
Molecular Weight 294.308 g/mol
InChI Key IAOZJIPTCAWIRG-QWRGUYRKSA-N
LogP 0.0904
Synonyms
  • Aspartame
  • Methyl L-alpha-aspartyl-L-phenylalaninate
  • L-Phenylalanine, L-alpha-aspartyl-, methyl ester
  • 22839-47-0
  • L-Phenylalanine, L-α-aspartyl-, 2-methyl ester
  • aspartam
  • aspartamo
  • Aspartylphenylalanine methyl ester
  • Canderel
  • Dipeptide sweetener
  • L-Aspartame
  • L-Aspartyl-L-3-phenylalanine methyl ester
  • L-Aspartyl-L-phenylalanine methyl ester
  • L-Aspartyl-L-phenylalanyl methyl ester
  • L-Phenylalanine, N-L-α-aspartyl-, 1-methyl ester
  • L-α-Aspartyl-L-phenylalanine methyl ester
  • Methyl aspartylphenylalanate
  • NutraSweet
  • Pal Sweet
  • Palsweet Diet
  • PHENYLALANINE (L), N-L-α-ASPARTYL-O-METHYL-
  • Succinamic acid, 3-amino-N-(α-carboxyphenethyl)-, N-methyl ester, stereoisomer
  • α-Aspartame
  • α-L-Aspartyl-L-phenylalanine methyl ester
  • α-Sweet
  • 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester, stereoisomer
  • 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid
  • Aspartame, L,L-alpha-
  • N-L-alpha-Aspartyl-L-phenylalanine 1-methyl ester
  • EINECS 245-261-3
  • Methyl L-alpha-aspartyl-L-phenylalanate
  • Methyl N-L-alpha-aspartyl-L-phenylalaninate
  • Methyl L-aspartyl-L-phenylalanine
  • 1-Methyl N-L-alpha-aspartyl-L-phenylalanine
  • Tri-sweet
  • Aspartamum
  • UNII-Z0H242BBR1
  • (3S)-3-amino-3-{[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid
  • 1-methyl N-L-alpha-aspartyl-L-phenylalanate
  • 3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester
  • 3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid
  • Asp-phe-ome
  • E 951
  • L-Aspartyl-L-phenylalanine methyl ester
  • Sweet dipeptide
  • 172964-81-7
  • 53906-69-7
  • 7421-84-3

Applications:


Bufferless Ion Separation (BLIS™) Chromatography of Aspartame: Organic Modifier Effect



An organic modifier effect of changing acetonitrile percentage the mobile phase is demonstrated on a Primesep C HPLC column in a bufferless ion (BLIS™) separation. With decreasing percent acetonitrile, the artificial sweetener, Aspartame, first deceases in retention time and then increases. The changing mobile phase composition changes the retention mechanism from hydrophobic and BLIS™interactions, to BLIS™ alone , to BLIS™ and HILIC (hydrophilic liquid chromatography) interactions. Aspartame is composed of the two amino acids, aspartic acid and phenylalanine as the ethyl ester. Mobile phases composed of water and acetonitrile (MeCN, ACN,) and ultraviolet (UV) detection was used.



Application Analytes:

Aspartame
Nutrasweet