Oxymetazoline

CAS Number 1491-59-4
Molecular Formula C16H24N2O
Molecular Weight 260.382 g/mol
InChI Key WYWIFABBXFUGLM-UHFFFAOYSA-N
LogP 4.01
Synonyms
  • Oxymetazoline
  • 6-tert-Butyl-3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,4-dimethylphenol
  • Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-
  • 1491-59-4
  • Phenol, 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-
  • 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline
  • 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
  • Navasin
  • Navisin
  • Nezeril
  • oximetazolina
  • Oxylazine
  • Oxymetazolin
  • Oxymethazoline
  • Phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-
  • Rhinofrenol
  • Rhinolitan
  • Sinerol
  • BRN 0886303
  • EINECS 216-079-1
  • Iliadin
  • Nafrine
  • Oximetazolinum
  • Oxymetazolinum
  • UNII-8VLN5B44ZY
  • 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol
  • 6-t-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol
  • Afrin

Applications:


Improved Peak Shape of a Basic Compound on Primesep B2 Column



Primesep B2 shows superior efficiency, symmetry, and peak shape for a hydrophilic basic compound compared to two leading reversed-phase C18 columns. Primesep B2 contains an embedded basic functional group that shields the underlying silica by ionic repulsion with the analyte. On reversed-phase columns exposed active silanols provide unintended polar interactions with basic analytes that lead to tailing. The HPLC separation uses a simple mobile phase of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with UV detection at 250 nm.



Application Analytes:

Oxymetazoline