p-Toluic Acid

p-Toluic Acid structural formula

CAS Number 99-94-5
Molecular Formula C8H8O2
Molecular Weight 136.150 g/mol
InChI Key LPNBBFKOUUSUDB-UHFFFAOYSA-N
LogP 2.27
Synonyms
  • 4-Methylbenzoic acid
  • Benzoic acid, 4-methyl-
  • 99-94-5
  • p-Toluic acid
  • Benzoic acid, 4-methyl-
  • Acide p-toluique
  • acido p-toluico
  • Crithminic acid
  • NSC 2215
  • p-Carboxytoluene
  • p-Methylbenzoic acid
  • p-Toluylic acid
  • p-Toluylsaure
  • p-Tolylcarboxylic acid
  • P-TOLYLSAEURE
  • TOLUIC ACID, PARA-
  • BRN 0507600
  • EINECS 202-803-3
  • UNII-A26GBX5SSV
  • 2420-97-5 (Cadmium salt)
  • 4-Methyl-Benzoic acid
  • 4-Toluic acid
  • Benzoic acid,4-methyl-
  • Crithmic acid
  • Toluate
  • para-Toluic acid
  • 852148-36-8

Applications:

Separation of Phthalic Acids and Related Impurities
 

Phthalic acid, phthalic acid isomers, and related products present in the production of phthalic acid were separated on the Primesep D column, based on reversed-phase and in-exchange mechanisms. Neutral, hydrophobic compounds of the phthalic acid production are retained by a reversed-phase mechanism, and phthalic acid and other acidic compounds are retained by a combination of reversed-phase and anion-exchange mechanisms. Resolution and selectivity of this separation can be modified by varying the amount of acetonitrile, buffer concentrations, and buffer pH. This method can be used for monitoring the production cycle of phthalic acid and related impurities.

 

Condition
Column Primesep D, 4.6x150 mm, 5 µm, 100A
Mobile Phase Gradient MeCN - 10-50%, 15 min
Buffer H2SO4 - 0.1%
Flow Rate 1.0 ml/min
Detection UV, 210 nm
 

Description
Class of Compounds Acid, Hydrophilic, Ionizable
Analyzing Compounds Terephthalaldehyde, Phthalic acid, 4-Carboxybenzaldehyde, Benzoic acid, Terephthalic acid, p –Tolualdehyde, p-Toluic acid
 
Application Analytes:

4-Carboxybenzaldehyde
Benzoic Acid
Phthalic Acid
Terephthalaldehyde
Terephthalic Acid
p-Tolualdehyde
p-Toluic Acid