Phenoxymethylpenicillin

CAS Number 87-08-1
Molecular Formula C16H18N2O5S
Molecular Weight 350.391 g/mol
InChI Key BPLBGHOLXOTWMN-MBNYWOFBSA-N
LogP 2.09
Synonyms
  • Penicillin V
  • (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, (2S,5R,6R)-
  • 87-08-1
  • 4-27-00-05884
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, (2S,5R,6R)-
  • [2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, [2S-(2α,5α,6β)]-
  • 6-(Phenoxyacetamido)penicillanic acid
  • Acipen-V
  • Calcipen
  • Crystapen V
  • Eskacillin V
  • Fenacilin
  • fenoximetilpenicilina
  • Meropenin
  • Oracillin
  • Oracilline
  • Oratren
  • Orocillin
  • Penicillin, phenoxymethyl-
  • Pen-Oral
  • Pen-Vee
  • Pen-vee-oral
  • Phenocillin
  • Phenopenicillin
  • Phenospen
  • phenoxymethylpenicillin
  • phenoxymethylpenicilline
  • Phenoxymethylpenicillinic acid
  • Stabicillin
  • V-Cillin
  • V-Cylina
  • V-Cyline
  • Vebecillin
  • V-Tablopen
  • Acipen V
  • BRN 0096259
  • Compocillin V
  • 3,3-Dimethyl-7-oxo-6-((phenyloxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
  • EINECS 201-722-0
  • Eskacillian V
  • Fenospen
  • P-Mega-Tablinen
  • Phenomycilline
  • Phenoximethylpenicillinum
  • Phenoxymethyl penicillin
  • Rocilin
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-
  • Fenossimetilpenicillina
  • Phenoxymethylpenicillinum
  • UNII-Z61I075U2W
  • (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 6-phenoxyacetamidopenicillanic acid
  • PV
  • penicillin phenoxymethyl
  • phenoxomethylpenicillin
  • phenoxymethylenepenicillinic acid
  • 11031-07-5
  • 6153-23-7

Applications:


HPLC Separation of Phenoxymethylpenicillin
   

Phenoxymethylpenicillin (also known as penicillin V) is an antibiotic useful in the treatment of multiple bacterial infections such as those caused by Streptococcus pyogenes, Anthrax, Lyme Disease, Rheumatic fever, and blood infection prophylaxis in children with sickle cell diseases.  Legacy L1 was used to retain Phenoxymethylpenicillin by reverse phase mechanism.Legacy L1 uses embedded C18 groups on porous silica and is useful for many USP HPLC applications. comparisons to Phenomenex columns are available by request.

 

Condition

Column Legacy L1, 4.6x250 mm, 5 µm, 100A
Mobile Phase MeCN - 30%
Buffer NaH2PO4 pH 6.0 - 30 mM
Flow Rate 1.0 ml/min
Detection UV, 270 nm

Description

Class of Compounds  Drug,  Hydrophobic, Ionizable
Analyzing Compounds Phenoxymethylpenicillin
&

Application Analytes:

Phenoxymethylpenicillin