Quinidine

CAS Number 56-54-2
Molecular Formula C20H24N2O2
Molecular Weight 324.424 g/mol
InChI Key LOUPRKONTZGTKE-LHHVKLHASA-N
LogP 3.44
Synonyms
  • Quinidine
  • (9S)-6'-Methoxycinchonan-9-ol
  • Cinchonan-9-ol, 6'-methoxy-, (9S)-
  • 56-54-2
  • Cinchonan-9-ol, 6'-methoxy-, (9S)-
  • (+)-Quinidine
  • (8R,9S)-Quinidine
  • 6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • Chinidin
  • Cin-quin
  • Conchinin
  • Conchinine
  • Conquinine
  • Kinidin
  • Pitayin
  • Pitayine
  • quinidina
  • Quinidine, (+)-
  • β-Quinidine
  • β-Quinine
  • EINECS 200-279-0
  • (9S)-6'-Methoxycinchonan-9-ol
  • alpha-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol (9S)-
  • (9S)-6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • NCI-C56246
  • UNII-ITX08688JL
  • (S)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinyl-2-quinuclidinyl]methanol
  • (S)-(6-methoxy-4-quinolyl)-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol
  • (S)-[(4S,5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol
  • 6-methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol
  • alpha-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol
  • beta-quinine
  • chinidinum
  • 11010-73-4
  • 500225-45-6
  • 845886-64-8
  • 882741-47-1
  • 883881-01-4
  • 898814-00-1
  • 910899-51-3
  • 1528764-92-2

Applications:


HPLC Separation of Quinine and Quinidine


Quinine and quinidine are diastreoisomers. Quinine is an alkaloid with fever-reducing analgetic and anti-inflammatory properties. Both compounds have the same structure, and the only difference is optical position at two centers. These two diastereoisomers were separated on achiral mixed-mode cation-exclusion Primesep B column. No separation is observed on traditional achiral reversed-phase column. This examples shows that even diastereoisomers can be separated on mixed-mode HPLC columns.



Application Analytes:

Hydroquinidine
Hydroquinone
Quinidine
Quinine