Quinine

CAS Number 130-95-0
Molecular Formula C20H24N2O2
Molecular Weight 324.424 g/mol
InChI Key LOUPRKONTZGTKE-WZBLMQSHSA-N
LogP 3.44
Synonyms
  • Quinine
  • (8alpha,9R)-6'-Methoxycinchonan-9-ol
  • Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
  • 130-95-0
  • Cinkona
  • Mosgard
  • Qualaquin
  • Quine 9
  • Quinex
  • Quinlex
  • Quinlup
  • Rezquin
  • Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
  • (-)-Quinine
  • (8S,9R)-Quinine
  • (8α,9R)-6'-Methoxycinchonan-9-ol
  • (R)-(-)-Quinine
  • 6'-Methoxycinchonidine
  • Chinine
  • NSC 192949
  • quinina
  • EINECS 205-003-2
  • (8-alpha,9R)-6'-Methoxycinchonan-9-ol
  • 6-Methoxycinchonine
  • Quinine anhydrous
  • 2-Quinuclidinemethanol, alpha-(6-methoxy-4-quinolyl)-5-vinyl-
  • (R)-(-)-Quinine, 6-methoxycinchonidine
  • UNII-A7V27PHC7A
  • (R)-(6-Methoxy-quinolin-4-yl)-((2S,5S)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
  • (R)-(6-methoxy-quinolin-4-yl)-((2S,5S)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
  • (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol
  • Chinin
  • chininum
  • 1071756-51-8
  • 12239-42-8
  • 128544-03-6
  • 21480-31-9
  • 55980-20-6
  • 6912-57-8
  • 72646-90-3
  • 767303-40-2
  • 840482-04-4
  • 857212-53-4
  • 864908-93-0
  • 875538-34-4
  • 888714-03-2
  • 890027-24-4
  • 894767-09-0
  • 898813-59-7
  • 898814-28-3
  • 899813-83-3
  • 900786-66-5
  • 900789-95-9
  • 906550-97-8
  • 909263-47-4
  • 909767-48-2
  • 909882-78-6
  • 910878-25-0
  • 910880-97-6
  • 911445-75-5
  • 918778-04-8
  • 95650-40-1
  • 1628705-47-4
  • 1267651-57-9

Applications:


HPLC Separation of Quinine and Quinidine


Quinine and quinidine are diastreoisomers. Quinine is an alkaloid with fever-reducing analgetic and anti-inflammatory properties. Both compounds have the same structure, and the only difference is optical position at two centers. These two diastereoisomers were separated on achiral mixed-mode cation-exclusion Primesep B column. No separation is observed on traditional achiral reversed-phase column. This examples shows that even diastereoisomers can be separated on mixed-mode HPLC columns.



Application Analytes:

Hydroquinidine
Hydroquinone
Quinidine
Quinine