Saccharin

CAS Number 81-07-2
Molecular Formula C7H5NO3S
Molecular Weight 183.180 g/mol
InChI Key CVHZOJJKTDOEJC-UHFFFAOYSA-N
LogP 0.91
Synonyms
  • Saccharin
  • 1H-1lambda6,2-Benzothiazole-1,1,3(2H)-trione
  • 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide
  • 81-07-2
  • 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide
  • 1,1-Dioxo-1,2-dihydro-1lambda6-benzo[d]isothiazol-3-one
  • [1,2-benzisothiazol-3(2H)-one, 1,1-dioxide]
  • 1,1-dioxido de 1,2-bencisotiazol-3(2H)-ona
  • 1,1-Dioxido-3-oxo-2,3-dihydrobenzo[d]isothiazole
  • 1,1-Dioxo-1,2-benzisothiazol-3(2H)-one
  • 1,1-Dioxyde de 1,2-benzisothiazol-3(2H)-one
  • 1,1-dioxyde de 1,2-benzisothiazole-3(2H)-one
  • 1,2-Benzisothiazol-3(2H)-on-1,1-dioxid
  • 1,2-benzisothiazol-3(2H)-one 1,1-dioxide
  • 1,2-Benzisothiazolin-3-one, 1,1-dioxide
  • 1,2-Benzothiazol-3(2H)-one 1,1-dioxide
  • 1,2-Dihydro-2-ketobenzisosulfonazole
  • 2,3-Dihydro-1,2-benzisothiazol-3-one-1,1-dioxide
  • 2,3-DIHYDRO-1,2-BENZOISOTHIAZOL-3-ONE 1,1-DIOXIDE
  • 2,3-Dihydro-3-oxobenzisosulfonazole
  • 3-Benzisothiazolinone 1,1-dioxide
  • 3-Hydroxybenzisothiazole-S,S-dioxide
  • 550 Saccharine
  • Anhydro-o-sulfaminebenzoic acid
  • Benzoic sulfimide
  • Benzoic sulphinide
  • Benzosulfimide
  • Benzosulfinide
  • Garantose
  • Gluside
  • NSC 5349
  • o-Benzoic acid sulfimide
  • o-Benzoic sulfimide
  • o-Benzosulfimide
  • o-Benzoyl sulfimide
  • o-Sulfobenzimide
  • o-Sulfobenzoic acid imide
  • Saccharimide
  • Saccharin acid
  • Saccharin insoluble
  • Saccharine
  • Saccharinol
  • Saccharinose
  • Saccharol
  • Benzosulfimide, O-
  • EINECS 201-321-0
  • RCRA waste number U202
  • Saccharina
  • Sulfobenzimide, O-
  • NSC 5731
  • UNII-FST467XS7D
  • 1, 2-Benzisothiazol-3(2H)-one, 1,1-dioxide
  • 1, 2-Benzisothiazolin-3-one 1,1-dioxide
  • 1, 2-Dihydro-2-ketobenzisosulfonazole
  • 1,1-Diox-1,2-benzisothiazol-3-one
  • 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one
  • 1,1-Dioxide-1,2-benzisothiazolin-3-one
  • 1,1-Dioxo-1,2-dihydro-1lambda*6*-benzo[D]isothiazol-3-one
  • 1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one
  • 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide
  • 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, 9CI
  • 1,2-Benzisothiazolin-3-one 1,1-dioxide
  • 1,2-Benzisothiazoline-3-one 1,1-dioxide
  • 1,2-Dihydro-2-ketobenzisosulphonazole
  • 2, 3-Dihydro-3-oxobenzisosulfonazole
  • 2,3-Dihydro-1,2-benzoisothiazol-3-one-1,1-dioxide
  • 2,3-Dihydro-3-oxo-Benzisosulfonazole
  • 2,3-Dihydro-3-oxobenzisosulphonazole
  • 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide
  • 2,3-dihydro-1λ⁶,2-benzothiazole-1,1,3-trione
  • 2-Sulfobenzoic acid imide
  • 2-Sulfobenzoicimide
  • 2-Sulphobenzoic imide
  • 3-Benzisothiazolinone 1, 1-dioxide
  • 3-Benzisothiazolinone 1,1-dioxide
  • 3-Hydroxybenzisothiazole S,S-dioxide
  • Benzo-2-sulfiide
  • Benzo-2-sulphimide
  • Benzo-sulphinide
  • Benzoic acid sulfimide
  • Benzoic sulfimide
  • Benzoic sulphimide
  • Benzosulphimide
  • Benzoylsulfonic Imide
  • E954
  • Glucid
  • Glycophenol
  • Hermesetas
  • Insoluble saccharin
  • Kandiset
  • LSA
  • Neosaccharin
  • O-Benzoic sulphimide
  • O-Benzosulphimide
  • O-Benzoyl sulphimide
  • O-Benzoylsulfimide
  • O-Sulfobenzoic imide
  • Sacarina
  • Saccharin (JP15/NF)
  • Saccharin [usan]
  • Saccharin, insoluble
  • Sacharin
  • Stilalgin
  • Sucre edulcor
  • Sucrette
  • Sweeta
  • Syncal
  • Zaharina
  • 126987-83-5
  • 474-91-9
  • 61255-27-4
  • 890126-34-8

Applications:


HPLC Separation of Saccharin and Sorbitol


Sorbitol and saccharin are two sugar substitutes used in food and drinks. Separation of sorbitol and saccharin was achieved on a Primesep N HILIC column using acetonitrile/water with ammonium formate. Compounds were monitored by combination of UV and ELSD. Method is compatible with LC/MS detection.



Application Analytes:

Saccharin

Separation of Alginic Acid and Related Products



Alginate is used in various pharmaceutical preparations. Chemically, it is a linear copolymer with homopolymeric blocks of (1-4)-linked ?-D-mannuronate (M) and its C-5 epimer ?-L-guluronate (G) residues, respectively, covalently linked together in different sequences or blocks. Alginic acid can be separated from benzoate, citric acid and saccharin by mixed-mode chromatography on Primesep C HPLC column. This method can be used to quantitate alginic acid, citric acid or saccharin in complex mixtures. Various detection technique can be used (UV, ELSD, LC/MS), based on mobile phase selection.



Application Analytes:

Alginic Acid
Benzoic Acid
Citric Acid
Saccharin