Streptomycin

Streptomycin structural formula

CAS Number 57-92-1
Molecular Formula C21H39N7O12
Molecular Weight 581.581 g/mol
InChI Key UCSJYZPVAKXKNQ-HZYVHMACSA-N
LogP -3.72
Synonyms
  • Streptomycin A
  • N,N'-[(1R,2R,3S,4R,5R,6S)-4-({5-Deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
  • Guanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-[[5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl]oxy]-2,5,6-trihydroxy-1,3-cyclohexanediyl]bis-
  • 57-92-1
  • D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1->4)-N,N'-bis(aminomethyl)-
  • 4-18-00-07540
  • D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-α-glucopyranosyl)-3-formylpentofuranoside
  • Agrimycin
  • D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N1,N3-bis(aminoiminomethyl)-
  • D-Streptamine,O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-
  • estreptomicina
  • Neodiestreptopab
  • NSC 14083
  • streptomycin
  • streptomycine
  • BRN 0074498
  • Caswell No. 804
  • 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
  • EINECS 200-355-3
  • EPA Pesticide Chemical Code 006306
  • Hokko-mycin
  • Strepcen
  • Streptomycinum
  • Streptomicina
  • Streptomyzin
  • UNII-Y45QSO73OB
  • SM
  • [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
  • streomycin
  • 364062-67-9
  • 47814-83-5
  • 47816-81-9
  • 82958-69-8

Applications:


HPLC Determination of Streptomycin on Primesep 200 Column
HPLC Determination of Streptomycin sulfate salt on Primesep 200 Column Streptomycin is an antibiotic used in treating bacterial infections and has also been used as a pesticide. It is on the World Health Organization’s (WHO) list of essential medicines. It works by inhibiting the synthesis of proteins. It can be retained on a Primesep 200 mixed-mode column by hydrophobic and ion-exchange properties. The analytical method uses MS-compatible mobile phase of acetonitrile (ACN) and water with sulfuric acid (H2SO4) buffer. Also capable of UV detection at 200nm.

Condition

Column Primesep 200, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 10/90%
Buffer H2SO4 - 0.05%
Flow Rate 1.0 ml/min
Detection UV, 200 nm
 

Description

Class of Compounds Drug, Hydrophilic, Zwitterionic, Antibiotic
Analyzing Compounds Streptomycin
 

Application Analytes:

Streptomycin
Streptomycin B
Streptothricins

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