Sucrose

CAS Number 57-50-1
Molecular Formula C12H22O11
Molecular Weight 342.297 g/mol
InChI Key CZMRCDWAGMRECN-UGDNZRGBSA-N
LogP -3.70
Synonyms
  • Sucrose
  • beta-D-Fructofuranosyl alpha-D-glucopyranoside
  • alpha-D-Glucopyranoside, beta-D-fructofuranosyl
  • 57-50-1
  • alpha-D-Glucopyranoside, beta-D-fructofuranosyl
  • D(+)-Sucrose
  • α-D-Glucopyranoside, β-D-fructofuranosyl
  • (+)-Sucrose
  • Amerfond
  • Beet sugar
  • Cane sugar
  • Carrare C 10
  • Confectioner's sugar
  • D-(+)-Saccharose
  • D-(+)-Sucrose
  • D-Sucrose
  • Frost Sugar
  • Granulated sugar
  • Khandsari
  • Manalox AS
  • Microse
  • NSC 406942
  • Rock candy
  • sacarosa
  • Saccharose
  • Saccharum
  • Sucralox
  • White sugar
  • α-D-GLUCOPYRANOSIDE, β-D- FRUCTOFURANOSYL
  • β-D-Fructofuranosyl α-D-glucopyranoside
  • β-D-Fructofuranosyl-α-D-glucopyranoside
  • Amerfand
  • EINECS 200-334-9
  • Fructofuranoside, alpha-D-glucopyranosyl, beta-D
  • beta-D-Fructofuranosyl alpha-D-glucopyranoside
  • Glucopyranoside, beta-D-fructofuranosyl, alpha-D
  • alpha-D-Glucopyranosyl beta-D-fructofuranoside
  • (alpha-D-Glucosido)-beta-D-fructofuranoside
  • NCI-C56597
  • Rohrzucker
  • Sucraloxum
  • UNII-C151H8M554
  • (2R,3R,4S,5R,6R)-2-[(2S,3S,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • (2R,3R,4S,5R,6R)-2-[(2S,3S,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl]oxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
  • (2R,3R,4S,5R,6R)-2-[(2S,3S,4R,5R)-3,4-dihydroxy-2,5-dimethylol-tetrahydrofuran-2-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol
  • (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
  • Sacharose
  • White sugar
  • b -D-Fructofuranosyl a-D-glucopyranoside
  • beta-D-Fruf-(2<->1)-alpha-D-Glcp
  • table sugar
  • 100405-08-1
  • 104242-10-6
  • 1159795-78-4
  • 12040-73-2
  • 1206156-82-2
  • 131932-12-2
  • 146054-35-5
  • 146187-04-4
  • 151756-02-4
  • 220376-22-7
  • 29253-78-9
  • 29764-06-5
  • 30027-72-6
  • 47167-52-2
  • 47185-09-1
  • 47257-91-0
  • 50857-68-6
  • 51909-69-4
  • 635681-90-2
  • 64533-66-0
  • 65545-99-5
  • 75398-84-4
  • 76056-38-7
  • 78654-77-0
  • 786702-63-4
  • 80165-03-3
  • 8027-47-2
  • 8030-20-4
  • 85456-51-5
  • 86101-30-6
  • 87430-66-8
  • 880257-62-5
  • 92004-84-7

Applications:


HPLC Analysis of Polysorbate in Mixture with Amino Acids and Sugar
Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are often used in cosmetics to solubilize essential oils into water-based products. Polysorbates are oily liquids derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids. Surfactants that are esters of plain (non-PEG-ylated) sorbitan with fatty acids are usually referred to by the name Span. It is often required to quantitate Polysorbate (Polysorbate/Tween 20, Polysorbate/Tween 40, Polysorbate 60/Tween 60 and Polysorbate 80) by HPLC in various formulations. Polysorbates exist in form of oligomers.

Condition

Column Primesep D, 3.2x50 mm, 5 µm, 100A
Mobile Phase IPA
Buffer Formic Acid
Flow Rate 0.5 ml/min
Detection ELSD
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Glycine, Histidine, Sucrose, Polysorbate 20


Application Analytes:

Amino Acids
Glycine
Histidine
Polysorbate
Polysorbate 20
Polysorbate 80
Sucrose
Tween 20
Tween 80

HPLC Separation of Barium Cation in the Presence of Citric Acid, Sucrose and Tween 80
chr_288.gif Barium ion and citric acid are analyzed in the presence of sucrose and Tween 80 on Obelisc N HILIC mixed-mode column. Both compounds are retained in ion-exchange mode and HILIC is not employed with this method. Obelisc N HPLC column has basic and acidic ion-exchange groups separated by long hydrophilic chain. Presence of that long chain allows both cation- and anion-exchange mechanisms to exist simultaneously. Obelisc N column can be used for analysis of cation and anions in HILIC/ion-exchange mode and in ion-exchange mode. Analytes can be monitored by ELSD/CAD and LC/MS.  

Condition

Column Obelisc N, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN
Buffer AmAc pH 4.0
Flow Rate 1.0 ml/min
Detection ELSD
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Description

Class of Compounds  Acid, Ion,  Hydrophobic, Ionizable
Analyzing Compounds Barium ion, Citric acid,  Sucrose, Tween 80


Application Analytes:

Citric Acid
Sucrose
Tween 80

HPLC Separation of Sugars on Primesep S2 Column
Five sugars were separated on a Primesep S2 HILIC column with LC/MS compatible conditions. Various mobile phase produce different selectivity and separation. Method can be used as alternative to aminopropyl column. Primesep S2 column is stable and does not undergo rapid hydrolysis like aminopropyl columns.

Condition

Column Primesep S2, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O
Buffer AmAc pH 5.0, Formic Acid
Flow Rate 1.0 ml/min
Detection ELSD 50C
 

Description

Class of Compounds Drug, Acid, Monocarboxylic acid,  Hydrophilic, Ionizable, Hormone
Analyzing Compounds Fructose, Glucose, Sucrose, Lactose, Maltose, Sorbitol, Sucrose, Alfa D-Lactose, Beta D–Lactose, Raffinose


Application Analytes:

Fructose
Glucose
Lactose
Maltose
Raffinose
Sorbitol
Sucrose
alpha-D-Lactose
beta-D-Lactose