Sulphanilamide

CAS Number	63-74-1
Molecular Formula	C6H8N2O2S
Molecular Weight	172.200 g/mol
InChI Key	FDDDEECHVMSUSB-UHFFFAOYSA-N
LogP	-0.620
Synonyms	Sulfanilamide 4-Aminobenzene-1-sulfonamide Benzenesulfonamide, 4-amino- 63-74-1 4-14-00-02658 Benzenesulfonamide, 4-amino- (4-(Aminosulfonyl)phenyl)amine 4-(Aminosulfonyl)aniline 4-Aminobenzenesulfonamide 4-Aminophenylsulfonamide 4-Aminosulfoneamide 4-Sulfamoylaniline Albexan Albosal Ambeside Antistrept Astreptine Astrocid Bacteramid Bactesid BENZENE SULFONAMIDE, 4-AMINO- Collomide Colsulanyde Copticide Deseptyl Ergaseptine Erysipan Estreptocida Exoseptoplix Fourneau 1162 Gerison Gombardol Infepan Lysococcine Neococcyl NSC 7618 Orgaseptine p-Aminobenzenesulfonamide p-Aminophenylsulfonamide p-Anilinesulfonamide Prontalbin Prontosil Album Prontosil I Prontosil white Prontylin Pronzin Album Proseptal Proseptine Proseptol p-Sulfamidoaniline p-Sulfamoylaniline Pysococcine Rubiazol A Sanamid Septamide Album Septanilam Septinal Septolix Septoplex Septoplix Stopton Album Stramid Strepamide Strepsan Streptagol Streptamid Streptasol Streptocid Streptocid album Streptocide Streptoclase Streptocom Strepton Streptopan Streptosil Streptozol Streptozone Sulfamidyl Sulfamine Sulfana Sulfanalone Sulfanidyl Sulfanil Sulfanilamid sulfanilamida Sulfanilamide Vaginal Cream Sulfocidine Sulfonamide Sulfonamide P Sulfonylamide sulphanilamide Sulphonamide Therapol White streptocide p-Aminobenzenesulfamide p-Aminobenzenesulfonylamide Aniline-p-sulfonic amide Benzenesulfonamide, p-amino- BRN 0511852 Caswell No. 809A EINECS 200-563-4 EPA Pesticide Chemical Code 077902 Streptamin Streptocide White Streptocidum Streptol Streptrocide Sulfanilimidic acid Sulfocidin Solfanilamide Sulfanilamidum UNII-21240MF57M 4-aminobenzene sulfonic acid amide 4-azanylbenzenesulfonamide SA para-aminobenzenesulfonamide 102489-34-9 12765-80-9 1337-36-6 1337-39-9 24706-25-0

Applications:

Separation of Antibiotics in Mixed-mode chromatography

A complex mixture of sulphonamide, macrolide, tetracycline and fluoroquinolone antibiotics were separated in one run using mixed-mode chromatography with LC/MS -compatible conditions. All compounds are separated based on reversed-phase and/or ion-exchange mechanism. Method can be used for analysis of various classes of antibiotics and related impurities in different sample matrices (blood, urine, soil, waste water).

Condition
Column	Obelisc R, 2.1x150 mm, 5 µm, 100A
Mobile Phase	Gradient MeCN - 0-25%, 6 min, 25-70% 14 min
Buffer	Gradient Formic Acid - 0.05%-0.3%, 10 min, 14 min hold
Flow Rate	1.0 ml/min
Detection	UV, 270 nm

Description
Class of Compounds	Antibiotic, Drug, Hydrophobic, Ionizable
Analyzing Compounds	Sulphanilamide, Sulphaguanidine, Oxytetracycline, Marbofloxacin, Sulphadiazine, Chlortetracycline, Nofloxacin, Spiramycin, Cefalonium, Tylosin, Josamycin, Sulphamethoxazole, Dapsone, Sulphaquinoxalline, Flumequine

Carboxymethylcysteine
Chlortetracycline
Dapsone
Flumequine
Josamycin
Marbofloxacin
Norfloxacin
Oxytetracycline
Spiramycin
Sulfamethoxazole
Sulfonamides
Sulphadiazine
Sulphaguanidine
Sulphanilamide
Sulphaquinoxaline
Tetracycline
Tylosin

Sulphanilamide

Applications:

Separation of Antibiotics in Mixed-mode chromatography

Condition

Description