Synephrine

CAS Number 94-07-5
Molecular Formula C9H13NO2
Molecular Weight 167.208 g/mol
InChI Key YRCWQPVGYLYSOX-UHFFFAOYSA-N
LogP -0.450
Synonyms
  • p-Synephrine
  • 4-[1-Hydroxy-2-(methylamino)ethyl]phenol
  • Benzenemethanol, 4-hydroxy-alpha-[(methylamino)methyl]-
  • 94-07-5
  • Analeptin
  • EINECS 202-300-9
  • Ethaphene
  • 4-Hydroxy-alpha-((methylamino)methyl)benzenemethanol
  • p-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol
  • p-Hydroxyphenylmethylaminoethanol
  • 1-(4-Hydroxyphenyl)-N-methylethanolamine
  • p-Methylaminoethanolphenol
  • beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol
  • Methylaminomethyl(4-hydroxyphenyl)carbinol
  • NSC 166285
  • p-Oxedrine
  • Parasympatol
  • Simpalon
  • Simpatol
  • Sympaethamine
  • Sympathol
  • Synthenate
  • alpha-(4-Oxyphenyl)alpha-oxy-beta-methylaminoaethan
  • Parakorper
  • Pentedrin
  • Synefrin
  • Sympaethamin
  • (+-)-N-Methyloctopamine
  • DL-Synephrine
  • NSC 170956
  • UNII-PEG5DP7434
  • (+/-)-Synephrine
  • 1-(4-Hydroxyphenyl)-2-(methylamino)ethanol
  • 1-(4-hydroxyphenyl)-2-methylaminoethanol
  • 4-hydroxy-alpha-[(methylamino)methyl]benzenemethanol
  • Oxedrine
  • Sympatol
  • Synephrine
  • beta-methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol
  • p-hydroxy-alpha-[(methylamino)methyl]benzyl alcohol

Applications:


HPLC Separation of Octopamine and Synephrine on Primesep 200 Column
HPLC Separation of Octopamine and Synephrine on Primesep 200 Column
Octopamine is an analog of norepinephrine in invertebrates that’s an important neurotransmitter and hormone. Synephrine is another molecule that has a similar structure to norepinephrine and is a very strong agonist of octopamine receptors in invertebrates. Both compounds can be baseline separated with an isocratic method in 30/70 Acetonitrile (ACN) and water mobile phase with a 30mM Ammonium Formate (AmFm) buffer at pH 3. UV detection 270nm.
 

Condition

Column Primesep 200, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 30/70%
Buffer AmFm pH 3.0- 30 mM
Flow Rate 1.0 ml/min
Detection UV, 270 nm
 

Description

Class of Compounds Drug, Acid, Hydrophilic, Ionizable,Neurotransmitter
Analyzing Compounds Octopamine, Synephrine
 

Application Analytes:

Octopamine
Synephrine