Trisamine

CAS Number 77-86-1
Molecular Formula C4H11NO3
Molecular Weight 121.137 g/mol
InChI Key LENZDBCJOHFCAS-UHFFFAOYSA-N
LogP -1.80
Synonyms
  • Tromethamine
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
  • 77-86-1
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
  • Tris(hydroxymethyl)aminomethane
  • [2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amine
  • 2-Amino-1,3-dihydroxy-2-(hydroxymethyl)propane
  • 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANDIOL
  • 2-Amino-2-(hydroxymethyl)-1,3-propanediol
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol
  • 2-Amino-2-hydroxymethyl-1, 3-propanediol
  • 2-amino-2-hydroxymethyl-1,3-propanediol
  • 2-Amino-2-hydroxymethylpropan-1,3-diol
  • 2-Amino-2-methylol-1,3-propanediol
  • Addex-Tham
  • Aminotri(hydroxymethyl)methane
  • Aminotrimethylolmethane
  • Aminotris(hydroxymethyl)methane
  • Methanamine, 1,1,1-tris(hydroxymethyl)-
  • NSC 103026
  • NSC 6365
  • NSC 65434
  • Pehanorm
  • PROPANE-1,3-DIOL, 2-AMINO-2-(HYDROXYMETHYL)-
  • Talatrol
  • Tri Amino
  • Tri(hydroxymethyl)methylamine
  • Trigmo base
  • TRIHYDROXYMETHYLAMINOMETHANE
  • Triladyl
  • Trimethylolaminomethane
  • TRIS
  • Tris Amino
  • Tris Amino Crystal
  • Tris base
  • TRIS BUFFER
  • Tris(hydroxymethyl)methanamine
  • TRIS(HYDROXYMETHYL)METHYLAMINE
  • Tris(methylolamino)methane
  • Tris, free base
  • Trisamin
  • Trisamine
  • Trisaminol
  • Trishydroxymethylaminomethane
  • Trispuffer
  • Tris-steril
  • Trometamol
  • Trometamole
  • Tromethane
  • Tromethanmin
  • Tutofusin tris
  • Apiroserum Tham
  • Caswell No. 036
  • EINECS 201-064-4
  • EPA Pesticide Chemical Code 083901
  • 2-(Hydroxymethyl)-2-amino-1,3-propanediol
  • Methylamine, 1,1,1-tris(hydroxymethyl)-
  • Tris-hydroxymethylaminomethane
  • Tromethamolum
  • Tris-hydroxymethyl-aminomethan
  • Trometamolum
  • UNII-023C2WHX2V
  • 1,1,1-tris(hydroxymethyl)methanamine
  • THAM
  • Tris-base
  • tris(hydroxymethyl)aminomethane
  • 108195-86-4
  • 1158650-64-6
  • 119320-15-9
  • 25149-07-9
  • 68755-45-3
  • 83147-39-1
  • 857365-23-2

Applications:


HPLC Separation of TRIS


TRIS or tris(hydroxymethyl)aminomethane, is a hydrophilic basic compounds widely used in chemistry, biochemistry, and molecular biology. TRIS pKa (8.1) makes it an effective buffer in pH range of 7-9.2. TRIS is not retained on reversed-phase column and is not UV active, making it hard to be analyzed by HPLC. TRIS was analyzed by mixed-mode HPLC on a Primesep 100 column. Retention time of compound is controlled by the amount and pH of the buffer. No ion-pairing reagent is required for HPLC retention of hydrophilic basic molecules like TRIS. TRIS can be monitored by ELSD/CAD with trifluoroacetic acid in the mobile phase, or by LC/MS with ammonium formate or acetate in the mobile phase.



Application Analytes:



TRIS (Tromethamine)
Trisamine