Vitamin B3 (Niacin)

CAS Number 59-67-6
Molecular Formula C6H5NO2
Molecular Weight 123.112 g/mol
InChI Key PVNIIMVLHYAWGP-UHFFFAOYSA-N
LogP 0.36
Synonyms
  • Nicotinic acid
  • Pyridine-3-carboxylic acid
  • 3-Pyridinecarboxylic acid
  • 59-67-6
  • Niacin
  • 5-22-02-00057
  • 3-Pyridinecarboxylic acid
  • 3-Carboxylpyridine
  • 3-Carboxypyridine
  • 3-Pyridylcarboxylic acid
  • Acide nicotinique
  • acido nicotinico
  • Apelagrin
  • Enduracin
  • Niaspan
  • Nicacid
  • Nicangin
  • Nicobid
  • Nicodelmine
  • Nicolar
  • Niconacid
  • Nico-Span
  • Nicotinipca
  • NICOTINSAEURE
  • Nicotinsaure
  • NSC 169454
  • Pellagrin
  • Pelonin
  • Slo-niacin
  • Wampocap
  • β-Pyridinecarboxylic acid
  • Acidum nicotinicum
  • BRN 0109591
  • Caswell No. 598
  • Davitamon PP
  • Direktan
  • EINECS 200-441-0
  • EPA Pesticide Chemical Code 056701
  • Nicagin
  • Nicocidin
  • Nicocrisina
  • Niconat
  • Niconazid
  • Nicosyl
  • Nicotamin
  • Nicotene
  • Nicotil
  • Nicotine acid
  • Nicovasan
  • Nicovasen
  • Nipellen
  • Pellagramin
  • Pyridine-beta-carboxylic acid
  • SK-Niacin
  • Tega-Span
  • Vitaplex N
  • Niaspan Titration Starter Pack
  • Kyselina nikotinova
  • Pyridine-carboxylique-3
  • UNII-2679MF687A
  • 3-Picolinic acid
  • 3-Pyridinecarboxylate
  • 3-Pyridylcarboxylate
  • Akotin
  • Daskil
  • Efacin
  • Induracin
  • Linic
  • Niac
  • Niacine
  • Niacor
  • Nicamin
  • Nicocap
  • Nicosan 3
  • Nicotinate
  • Nicyl
  • Nikotinsaeure
  • Nyclin
  • P.P. factor
  • PP factor
  • Pellagrin
  • Peviton
  • Tinic
  • anti-pellagra vitamin
  • beta-pyridinecarboxylic acid
  • m-pyridinecarboxylic acid
  • pellagra preventive factor
  • pyridine-3-carboxylic acid
  • pyridine-beta-carboxylic acid
  • vitamin B3
  • 123574-58-3

Applications:


HILIC Separation of Vitamins Group B
Separation of vitamins group B is achieved on Obelisc N column in HILIC mixed-mode. Vitamins of this group are different in polarity and ionic properties. Retention and separation is achieved by optimization of amount of ACN, buffer and buffer pH. Combination of UV and ELSD detection is used to monitor HPLC separation. B vitamins are water-soluble vitamins that play an important role in cell metabolism. Supplements containing all six are generally referred to as a vitamin B complex. Individual B vitamin supplements are referred to by the specific name of each vitamin. This method can be used to analyze individual B vitamins as well as vitamin B complex. Isolation of impurities as well as degradation products is possible by preparative chromatography.

Application Analytes:

Nicotinic Acid
Vitamin B1 (Thiamine)
Vitamin B2 (Riboflavin)
Vitamin B3 (Niacin)
Vitamin B5 (Pantothenic Acid)
Vitamin B6 (Pyridoxine)

USP Methods for the Analysis of Niacin with the Legacy L1 Column
Niacin (vitamin B3, nicotinic acid) is one of the essential vitamins. The water-soluble vitamin was analyzed by reversed-phase chromatography on the C18 reversed-phase HPLC column, Legacy L1. This column is classified according to USP as a L1-type of column. It can be used for the analysis of various drugs, vitamins, and chemicals according to United States Pharmacopeia.

Condition

Column Legacy L1, 4.6x150 mm, 5 µm, 100A
Mobile Phase Hexanesulfonate/MeOH/MeCN/AcOH –78/14/7/2
Buffer Hexanesulfonate
Flow Rate 1.0 ml/min
Detection UV, 250 nm
 

Description

Class of Compounds Drug, Cholesterol medication, Vitamin B3, Hydrophobic, Ionizable
Analyzing Compounds Vitamin B3, Niacin
 

Application Analytes:

Vitamin B3 (Niacin)