Vitamin E Acetate

CAS Number 58-95-7
Molecular Formula C31H52O3
Molecular Weight 472.754 g/mol
InChI Key ZAKOWWREFLAJOT-CEFNRUSXSA-N
LogP 10.3
Synonyms
  • D-alpha-Tocopheryl acetate
  • (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-
  • 58-95-7
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-
  • (+)-α-Tocopherol acetate
  • (+)-α-Tocopheryl acetate
  • (2R,4'R,8'R)-α-Tocopherol acetate
  • (2R,4'R,8'R)-α-Tocopheryl acetate
  • (R,R,R)-α-Tocopheryl acetate
  • 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, 6-acetate, (2R)-
  • 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
  • Acetate d'α-tocopheryle
  • acetato de α-tocoferilo
  • Combinal E
  • Copherol 12250
  • Copherol 1250
  • Covitol
  • Covitol 1100
  • Covitol 1360
  • Covitol 700
  • Covitol 700WD
  • d-Vitamin E acetate
  • D-α-Tocopherol acetate
  • D-α-TOCOPHERYL ACETATE
  • E 230 Clear
  • E-Toplex
  • E-Vicotrat
  • Evipherol
  • Lutavit E 50
  • Nanotopes
  • Natur-E granulate
  • Spondyvit
  • Tinoderm E
  • TOCOPHEROL ACETATE, (+)-α-
  • TOCOPHERYL ACETATE
  • TOCOPHERYL ACETATE, D-α-
  • TOCOPHERYL D-α ACETATE
  • Tokoferol acetate
  • Vitamin E 230 Clear
  • Vitamin Eα acetate
  • α-Tocopherylacetat
  • Alfacol
  • 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
  • Contopheron
  • 6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
  • 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
  • Ecofrol
  • EINECS 200-405-4
  • Ephynal acetate
  • Epsilan-M
  • E-Ferol
  • 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
  • Tocopherex
  • (+)-alpha-Tocopherol acetate
  • d-alpha-Tocopherol acetate
  • alpha-Tocopherol acetate, (2R,4'R,8'R)-
  • (+)-alpha-Tocopheryl acetate
  • (R,R,R)-alpha-Tocopheryl acetate
  • (2R,4'R,8'R)-alpha-Tocopheryl acetate
  • Tocophrin
  • Tofaxin
  • Endo E Dompe
  • Vitamin Ealpha acetate
  • Vitamin E acetate, d-
  • UNII-A7E6112E4N
  • Simmyungsaengmosu
  • 12741-00-3
  • 1406-70-8
  • 26243-95-8

Applications:


HPLC Separation of Vitamin E and Vitamin E Acetate



Primesep B separates Vitamin E and Vitamin E acetate with reversed peak order of a traditional C8 column. The different selectivity is due to an embedded basic functional group on the stationary phase which contributes polar interactions to the separation. Excellent peak shape results with a mass spec compatible mobile phase of water and acetonitrile (MeCN, ACN) with UV detection at 205 nm.



Application Analytes:

Vitamin E
Vitamin E Acetate

HPLC Analysis of ACE Serum Active Ingredients


Mixed-mode HPLC columns allow for separation of compounds with drastically different properties. In this application, highly hydrophilic ascorbic acid is retained and separated from highly hydrophobic retinol and Vitamin E Acetate. Ascorbic acid is retained by anion-exchange mechanism and hydrophobic compounds are retained by reversed-phase mechanism. Compounds are monitored by UV detection. Mobile phase is compatible with LC/MS and method can be used to monitor basic and acidic compounds in bio-fluids (serum, blood, urine, saliva, etc.)



Application Analytes:

Ascorbic Acid
Vitamin E Acetate