Zemuron

CAS Number 119302-91-9
Molecular Formula C32H53BrN2O4
Molecular Weight 609.691 g/mol
InChI Key OYTJKRAYGYRUJK-FMCCZJBLSA-M
LogP 1.86
Synonyms
  • Rocuronium bromide
  • (2beta,3alpha,5alpha,16beta,17beta)-17-(Acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidin-1-ium-1-yl]androstane bromide
  • Androstane-3,17-diol, 2-(4-morpholinyl)-16-[1-(2-propen-1-yl)-1-pyrrolidiniumyl]-, bromide, 17-acetate, (2beta,3alpha,5alpha,16beta,17beta)- (1:1)
  • 119302-91-9
  • Pyrrolidinium, 1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
  • UNII-I65MW4OFHZ
  • 1-Allyl-1-(3alpha,17beta-dihydroxy-2beta-morpholino-5alpha-androstan-16beta-yl)pyrrolidinium bromide, 17-acetate
  • 17beta-acetoxy-16beta-(1-allylpyrrolidinium-1-yl)-3alpha-hydroxy-2beta-(morpholin-4-yl)-5alphaandrostane

Applications:


Separation Study of Zemuron Active Ingredient in Mixed-Mode HPLC


Zemuron is an amino steroid used as a muscle relaxant during anesthesia. Zemuron was analyzed by mixed-mode chromatography on a Primesep C HPLC column. Compound is hydrophobic and basic in nature, and retention time on cation-exchange mixed-mode column is controlled by the amount of acetonitrile, buffer concentration and buffer pH. In order to observe cation-exchange interaction on a Primesep C column, mobile phase pH should be maintained between 3-7.



Application Analytes:

Zemuron