Cortisone 21-Acetate

CAS Number50-04-4
Molecular FormulaC23H30O6
Molecular Weight402.5
InChI KeyITRJWOMZKQRYTA-RFZYENFJSA-N
LogP2.1
Synonyms
  • CORTISONE ACETATE
  • Cortisone 21-acetate
  • 50-04-4
  • Cortone acetate
  • Incortin
  • Biocort acetate
  • Artriona
  • Cortadren
  • Scheroson
  • Cortisyl
  • Adreson
  • Irisone acetate
  • Cortelan
  • Cortistab
  • Ricortex
  • Corlin
  • Cortogen acetate
  • Compound E acetate
  • Cortisone (acetate)
  • Cortisone monoacetate
  • NSC 49420
  • Cortisone, 21-acetate
  • Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-
  • Cortilen
  • UNII-883WKN7W8X
  • 11-Dehydro-17-hydroxycorticosterone-21-acetate
  • CCRIS 3661
  • 11-Dehydro-17-hydroxycorticosterone acetate
  • EINECS 200-006-5
  • 17,21-Dihydroxypregn-4-ene-3,11,20-trione 21-acetate
  • 883WKN7W8X
  • CHEBI:3897
  • Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate
  • ITRJWOMZKQRYTA-RFZYENFJSA-N
  • MFCD00003609
  • 21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione
  • 21-Acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4
  • 21-Acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione
  • NCGC00021191-07
  • 4-Pregnene-17,alpha,21-diol-3,11,20-trione 21-acetate
  • DSSTox_CID_2858
  • DSSTox_RID_76761
  • DSSTox_GSID_22858
  • 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate
  • 21-Acetoxy-4-pregnen-17alpha-ol-3,11,20-trione
  • Cortisone 21-acetate, 98+%
  • 17,21-Dihydroxypregn-4-ene-3,11,20-trione-21-acetate
  • 17alpha,21-dihydroxypregn-4-ene-3,11,20-trione acetate
  • CAS-50-04-4
  • [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
  • [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
  • 2-((1S,10S,11S,15S,2R,14R)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0 .0<2,7>.0<11,15>]heptadec-6-en-14-yl)-2-oxoethyl acetate
  • 2-((8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
  • SMR000059124
  • Cortisone acetate (Cortone)
  • Cortisone acetate [USP:JAN]
  • Cortisone acetate [USAN:JAN]
  • Acetate cortisone
  • Cortisyl artriona
  • component of Neosone
  • Neosone (Salt/Mix)
  • Cortisone-21-acetate
  • Cortone acetate (TN)
  • Cortisone-acetate-Cortone
  • AC1L1L1N
  • AC1Q62MF
  • SCHEMBL4501
  • CHEMBL1650
  • Lopac0_000271
  • MLS000069478
  • MLS002207136
  • MLS002548859
  • ARONIS24358
  • Cortisone acetate (JP17/USP)
  • DTXSID0022858
  • CTK8D6790
  • Cortisone 21-acetate, >=99%
  • HMS2235D24
  • HMS3259N19
  • HMS3260H04
  • BCP08487
  • NSC49420
  • ZINC3875334
  • Tox21_113482
  • Tox21_500271
  • BDBM50455157
  • HY-17461A
  • LMST02030120
  • NSC-49420
  • SBB080776
  • AKOS005267225
  • Tox21_113482_1
  • AC-6827
  • AN-9606
  • CCG-204366
  • CS-1742
  • DB01380
  • LP00271
  • MCULE-8390750975
  • NC00677
  • NCGC00021191-03
  • NCGC00021191-06
  • NCGC00021191-08
  • NCGC00021191-09
  • NCGC00260956-01
  • AK163492
  • AS-13692
  • CC-25981
  • LS-55003
  • ST075179
  • AB2000655
  • EU-0100271
  • FT-0665176
  • S2559
  • ST24046370
  • C08173
  • D00973
  • J10115
  • AB00384283-08
  • AB00384283_09
  • 003C609
  • C-21758
  • W-105993
  • BRD-K86161929-001-13-3
  • Pregn-4-ene-3,20-trione, 21-(acetyloxy)-17-hydroxy-
  • 17-Hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate
  • #21-Acetoxy-17.alpha.-hydroxy-3,11,20-triketopregnene-4
  • 21-Acetoxy-17.alpha.-hydroxypregn-4-ene-3,11,20-trione
  • 4-Pregnen-17.alpha.,21-diol-3,11,20-trione 21-acetate
  • 4-Pregnene-17alpha,21-diol-3,11,20-trione 21-acetate
  • Pregn-4-ene-3,20-trione, 17,21-dihydroxy-, 21-acetate
  • 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate
  • 4-Pregnene-17.alpha.,21-diol-3,11,20-trione 21-acetate
  • Cortisone acetate, European Pharmacopoeia (EP) Reference Standard
  • Cortisone acetate, United States Pharmacopeia (USP) Reference Standard

Applications:

HPLC Method for Analysis of Sulfadiazine, Naphthylthiourea, Sulfamethazine, Dexamethasone, Cortisone 21-Acetate

July 11, 2017

Sulfadiazine is an antibiotic used to prevent rheumatic fever, chancroid, chlamydia and infections by Haemophilus influenzae. There are side effects to the use of the drug which include, but not limited to: nausea, headache, rash, depression.

 

Condition

Column Primesep 100, 3.2×50 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 20-75%, 4 min
Buffer Gradient H3PO4 – 0.05-0.2%, 4 min
Flow Rate 0.5 ml/min
Detection UV, 270 nm

 

Description

Class of Compounds
Drug, Acid, Hydrophilic, Ionizable
Analyzing Compounds Sulfadiazine, Naphthylthiourea, Sulfamethazine, Dexamethasone, Cortisone 21-Acetate

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Cortisone 21-Acetate
Dexamethasone
Naphthylthiourea
Sulfadiazine
Sulfamethazine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.