Cyanoacetic acid

Cyanoacetic acid structural formula

CAS Number372-09-8
Molecular FormulaC3H3NO2
Molecular Weight85.062
InChI KeyMLIREBYILWEBDM-UHFFFAOYSA-N
LogP-0.760
Synonyms
  • Cyanoacetic acid
  • Acetic acid, 2-cyano-
  • 372-09-8
  • 4-02-00-01888
  • Acetic acid, cyano-
  • 2-Cyanoacetic acid
  • Acetic acid, 2-cyano-
  • ACETIC ACID, CYANO
  • Acide cyanoacetique
  • acido cianoacetico
  • CYANESSIGSAEURE
  • Cyanessigsaure
  • Cyanoethanoic acid
  • Malonic mononitrile
  • Monocyanoacetic acid
  • NSC 5571
  • BRN 0506325
  • EINECS 206-743-9
  • Acide cyanacetique
  • Kyselina kyanoctova
  • UNII-QZT550H2Y9
  • Malonic acid mononitrile

Applications:

HPLC Determination of Cyanoacetic Acid on Primesep SB Column

October 1, 2019


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HPLC Determination of Cyanoacetic Acid on Primesep SB Column_1187

Condition

Column Primesep SB, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 20/80%
Buffer H2SO4 – 0.05%
Flow Rate 1.0 ml/min
Detection UV, 200 nm

Description

Class of Compounds Acid, Hydrophilic, Ionizable
Analyzing Compounds Cyanoacetic Acid

Application Column

Primesep SB

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
Cyanoacetic acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Cyanoacetic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Cyanoacetic acid on Newcrom C18 HPLC column

Cyanoacetic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Cyanoacetic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.